PDB entry 3ir2

View 3ir2 on RCSB PDB site
Description: Crystal structure of the APOBEC3G catalytic domain
Class: hydrolase
Keywords: APOBEC3G, ANTIVIRAL DEFENSE, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, Nucleus
Deposited on 2009-08-21, released 2010-01-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.168
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA dC->dU-editing enzyme APOBEC-3G
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC3G, MDS019
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC16
      • engineered (56)
      • engineered (65)
      • engineered (132)
      • engineered (143)
      • engineered (178)
    Domains in SCOPe 2.08: d3ir2a_
  • Chain 'B':
    Compound: DNA dC->dU-editing enzyme APOBEC-3G
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC3G, MDS019
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HC16
      • engineered (56)
      • engineered (65)
      • engineered (132)
      • engineered (143)
      • engineered (178)
    Domains in SCOPe 2.08: d3ir2b_
  • Heterogens: ZN, CL, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ir2A (A:)
gplgspefelgtteilrhsmdpptftfnfnnepwvrgrhetylcyevermhndtwvklnq
rrgflanqaphkhgflegrhaelcfldvipfwkldldqdyrvtcftswspcfscaqemak
fisknkhvslciktariyddqgraqeglrtlaeagakisimtysefkhcwdtfvdhqgap
fqpwdgldehsqdlsgrlrailqnqen

    Sequence, based on observed residues (ATOM records): (download) 
    >3ir2A (A:)
rhsmdpptftfnfnnepwvrgrhetylcyevermhndtwvklnqrrgflanqaphkhgfl
egrhaelcfldvipfwkldldqdyrvtcftswspcfscaqemakfisknkhvslciktar
iyddqgraqeglrtlaeagakisimtysefkhcwdtfvdhqgapfqpwdgldehsqdlsg
rlrailqn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ir2B (B:)
gplgspefelgtteilrhsmdpptftfnfnnepwvrgrhetylcyevermhndtwvklnq
rrgflanqaphkhgflegrhaelcfldvipfwkldldqdyrvtcftswspcfscaqemak
fisknkhvslciktariyddqgraqeglrtlaeagakisimtysefkhcwdtfvdhqgap
fqpwdgldehsqdlsgrlrailqnqen

    Sequence, based on observed residues (ATOM records): (download) 
    >3ir2B (B:)
hsmdpptftfnfnnepwvrgrhetylcyevermhndtwvklnqrrgflanqaphkhgfle
grhaelcfldvipfwkldldqdyrvtcftswspcfscaqemakfisknkhvslciktari
yddqgraqeglrtlaeagakisimtysefkhcwdtfvdhqgapfqpwdgldehsqdlsgr
lrailqn