PDB entry 3imz

View 3imz on RCSB PDB site
Description: Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human Pex5p
Class: transferase/transport protein
Keywords: TPR-domain, protein-protein complex, peroxisome, Aminotransferase, Pyruvate, Transferase, Disease mutation, Membrane, Peroxisome biogenesis disorder, Protein transport, TPR repeat, Transport, Zellweger syndrome, TRANSFERASE-TRANSPORT PROTEIN COMPLEX, Mitochondrion, Pyridoxal phosphate
Deposited on 2009-08-11, released 2010-08-18
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-05-11, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.184
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alanine--glyoxylate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT1, AGXT, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imza_
  • Chain 'B':
    Compound: peroxisomal targeting signal 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: PEX5, PXR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imzb_
  • Chain 'C':
    Compound: alanine--glyoxylate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT1, AGXT, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imzc_
  • Chain 'D':
    Compound: peroxisomal targeting signal 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: PEX5, PXR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imzd_
  • Heterogens: BTB, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3imzA (A:)
    gamashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimd
    eikegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdiger
    igarvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykc
    lllvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpf
    sfyldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaayl
    hgrlqalglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkv
    lrigllgcnatrenvdrvtealraalqhcpkkkl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3imzA (A:)
    llvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikegiq
    yvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarvhp
    mtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvdsv
    aslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyldik
    wlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlqal
    glqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigllg
    cnatrenvdrvtealraalqhcpkkkl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3imzB (B:)
    gamltsatydkgyqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmea
    wqylgttqaeneqellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlr
    ytpayahlvtpaeegaggaglgpskrilgsllsdslflevkelflaavrldptsidpdvq
    cglgvlfnlsgeydkavdcftaalsvrpndyllwnklgatlangnqseeavaayrralel
    qpgyirsrynlgiscinlgahreavehflealnmqrksrgprgeggamseniwstlrlal
    smlgqsdaygaadardlstlltmfglpq
    

    Sequence, based on observed residues (ATOM records): (download)
    >3imzB (B:)
    qfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmeawqylgttqaeneq
    ellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlrytpayahlvdslf
    levkelflaavrldptsidpdvqcglgvlfnlsgeydkavdcftaalsvrpndyllwnkl
    gatlangnqseeavaayrralelqpgyirsrynlgiscinlgahreavehflealnmqrk
    srrgeggamseniwstlrlalsmlgqsdaygaadardlstlltmfglpq
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3imzC (C:)
    gamashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimd
    eikegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdiger
    igarvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykc
    lllvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpf
    sfyldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaayl
    hgrlqalglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkv
    lrigllgcnatrenvdrvtealraalqhcpkkkl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3imzC (C:)
    hkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikeg
    iqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarv
    hpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvd
    svaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyld
    ikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlq
    alglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigl
    lgcnatrenvdrvtealraalqhcpkkkl
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3imzD (D:)
    gamltsatydkgyqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmea
    wqylgttqaeneqellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlr
    ytpayahlvtpaeegaggaglgpskrilgsllsdslflevkelflaavrldptsidpdvq
    cglgvlfnlsgeydkavdcftaalsvrpndyllwnklgatlangnqseeavaayrralel
    qpgyirsrynlgiscinlgahreavehflealnmqrksrgprgeggamseniwstlrlal
    smlgqsdaygaadardlstlltmfglpq
    

    Sequence, based on observed residues (ATOM records): (download)
    >3imzD (D:)
    yqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmeawqylgttqaene
    qellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlrytpayahlvtpa
    sllsdslflevkelflaavrldptsidpdvqcglgvlfnlsgeydkavdcftaalsvrpn
    dyllwnklgatlangnqseeavaayrralelqpgyirsrynlgiscinlgahreavehfl
    ealnmqrksgamseniwstlrlalsmlgqsdaygaadardlstlltmfglpq