PDB entry 3imz

View 3imz on RCSB PDB site
Description: Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human Pex5p
Class: transferase/transport protein
Keywords: TPR-domain, protein-protein complex, peroxisome, Aminotransferase, Pyruvate, Transferase, Disease mutation, Membrane, Peroxisome biogenesis disorder, Protein transport, TPR repeat, Transport, Zellweger syndrome, TRANSFERASE-TRANSPORT PROTEIN COMPLEX, Mitochondrion, Pyridoxal phosphate
Deposited on 2009-08-11, released 2010-08-18
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-05-11, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.184
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alanine--glyoxylate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT1, AGXT, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imza_
  • Chain 'B':
    Compound: peroxisomal targeting signal 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: PEX5, PXR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imzb_
  • Chain 'C':
    Compound: alanine--glyoxylate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT1, AGXT, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imzc_
  • Chain 'D':
    Compound: peroxisomal targeting signal 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: PEX5, PXR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3imzd_
  • Heterogens: BTB, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3imzA (A:)
gamashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimd
eikegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdiger
igarvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykc
lllvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpf
sfyldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaayl
hgrlqalglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkv
lrigllgcnatrenvdrvtealraalqhcpkkkl

    Sequence, based on observed residues (ATOM records): (download) 
    >3imzA (A:)
llvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikegiq
yvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarvhp
mtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvdsv
aslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyldik
wlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlqal
glqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigllg
cnatrenvdrvtealraalqhcpkkkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3imzB (B:)
gamltsatydkgyqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmea
wqylgttqaeneqellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlr
ytpayahlvtpaeegaggaglgpskrilgsllsdslflevkelflaavrldptsidpdvq
cglgvlfnlsgeydkavdcftaalsvrpndyllwnklgatlangnqseeavaayrralel
qpgyirsrynlgiscinlgahreavehflealnmqrksrgprgeggamseniwstlrlal
smlgqsdaygaadardlstlltmfglpq

    Sequence, based on observed residues (ATOM records): (download) 
    >3imzB (B:)
qfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmeawqylgttqaeneq
ellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlrytpayahlvdslf
levkelflaavrldptsidpdvqcglgvlfnlsgeydkavdcftaalsvrpndyllwnkl
gatlangnqseeavaayrralelqpgyirsrynlgiscinlgahreavehflealnmqrk
srrgeggamseniwstlrlalsmlgqsdaygaadardlstlltmfglpq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3imzC (C:)
gamashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimd
eikegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdiger
igarvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykc
lllvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpf
sfyldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaayl
hgrlqalglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkv
lrigllgcnatrenvdrvtealraalqhcpkkkl

    Sequence, based on observed residues (ATOM records): (download) 
    >3imzC (C:)
hkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikeg
iqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarv
hpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvd
svaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyld
ikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlq
alglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigl
lgcnatrenvdrvtealraalqhcpkkkl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3imzD (D:)
gamltsatydkgyqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmea
wqylgttqaeneqellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlr
ytpayahlvtpaeegaggaglgpskrilgsllsdslflevkelflaavrldptsidpdvq
cglgvlfnlsgeydkavdcftaalsvrpndyllwnklgatlangnqseeavaayrralel
qpgyirsrynlgiscinlgahreavehflealnmqrksrgprgeggamseniwstlrlal
smlgqsdaygaadardlstlltmfglpq

    Sequence, based on observed residues (ATOM records): (download) 
    >3imzD (D:)
yqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmeawqylgttqaene
qellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlrytpayahlvtpa
sllsdslflevkelflaavrldptsidpdvqcglgvlfnlsgeydkavdcftaalsvrpn
dyllwnklgatlangnqseeavaayrralelqpgyirsrynlgiscinlgahreavehfl
ealnmqrksgamseniwstlrlalsmlgqsdaygaadardlstlltmfglpq