PDB entry 3il1

View 3il1 on RCSB PDB site
Description: Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, IDRA-21
Class: membrane protein
Keywords: glutamate receptor, glur2, AMPA receptor, neurotransmitter receptor, S1S2, allosteric modulator, Alternative splicing, Cell junction, Cell membrane, Endoplasmic reticulum, Glycoprotein, Ion transport, Ionic channel, Lipoprotein, Membrane, Palmitate, Phosphoprotein, Postsynaptic cell membrane, Receptor, RNA editing, Synapse, Transmembrane, Transport, MEMBRANE PROTEIN
Deposited on 2009-08-06, released 2009-09-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Glur2, Gria2, Gria2; GluR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (0-113)
      • linker (114-115)
    • Uniprot P19491 (116-257)
      • engineered (238)
    Domains in SCOPe 2.07: d3il1b_
  • Chain 'E':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Glur2, Gria2, Gria2; GluR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (0-113)
      • linker (114-115)
    • Uniprot P19491 (116-257)
      • engineered (238)
    Domains in SCOPe 2.07: d3il1e_
  • Chain 'H':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Glur2, Gria2, Gria2; GluR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (0-113)
      • linker (114-115)
    • Uniprot P19491 (116-257)
      • engineered (238)
    Domains in SCOPe 2.07: d3il1h_
  • Heterogens: GLU, ZN, B5D, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3il1B (B:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklse
qglldklknkwwydkgec

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3il1E (E:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklse
qglldklknkwwydkgec

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3il1H (H:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklse
qglldklknkwwydkgec