PDB entry 3ihf

View 3ihf on RCSB PDB site
Description: Crystal structure of mouse Bcl-xl mutant (R139A) at pH 5.0
Class: apoptosis
Keywords: Apoptosis, BH3 domain, Bcl-2, Membrane, Mitochondrion, Transmembrane
Deposited on 2009-07-30, released 2010-04-14
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-11-20, with a file datestamp of 2013-11-15.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: 0.197
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bcl-2-like protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Bcl-xl, Bcl2l, Bcl2l1, Bclx
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q64373 (Start-195)
      • engineered (138)
    Domains in SCOPe 2.05: d3ihfa_
  • Chain 'B':
    Compound: Bcl-2-like protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Bcl-xl, Bcl2l, Bcl2l1, Bclx
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q64373 (Start-195)
      • engineered (138)
    Domains in SCOPe 2.05: d3ihfb_
  • Chain 'C':
    Compound: Bcl-2-like protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Bcl-xl, Bcl2l, Bcl2l1, Bclx
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q64373 (Start-195)
      • engineered (138)
    Domains in SCOPe 2.05: d3ihfc_
  • Chain 'D':
    Compound: Bcl-2-like protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Bcl-xl, Bcl2l, Bcl2l1, Bclx
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q64373 (Start-195)
      • engineered (138)
    Domains in SCOPe 2.05: d3ihfd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ihfA (A:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvsriaswmatylndhlep
wiqenggwdtfvdlyg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ihfA (A:)
sqsnrelvvdflsyklsqkgyswsqfsdssldarevipmaavkqalreagdefelryrra
fsdltsqlhitpgtayqsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvs
riaswmatylndhlepwiqenggwdtfvdlyg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ihfB (B:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvsriaswmatylndhlep
wiqenggwdtfvdlyg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ihfB (B:)
sqsnrelvvdflsyklsqkgyswsqfsdssldarevipmaavkqalreagdefelryrra
fsdltsqlhitpgtayqsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvs
riaswmatylndhlepwiqenggwdtfvdlyg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3ihfC (C:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvsriaswmatylndhlep
wiqenggwdtfvdlyg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ihfC (C:)
sqsnrelvvdflsyklsqkgyswsqfsdssldarevipmaavkqalreagdefelryrra
fsdltsqlhitpgtayqsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvs
riaswmatylndhlepwiqenggwdtfvdlyg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3ihfD (D:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteaeretpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvsriaswmatylndhlep
wiqenggwdtfvdlyg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ihfD (D:)
sqsnrelvvdflsyklsqkgyswsqfsdssldarevipmaavkqalreagdefelryrra
fsdltsqlhitpgtayqsfeqvvnelfrdgvnwgaivaffsfggalcvesvdkemqvlvs
riaswmatylndhlepwiqenggwdtfvdlyg