PDB entry 3ifw
View 3ifw on RCSB PDB site
Description: Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester.
Class: hydrolase/hydrolase inhibitor
Keywords: Enzyme-suicide substrate complex, Cytoplasm, Disease mutation, Glycoprotein, Hydrolase, Ligase, Oxidation, Polymorphism, Protease, Thiol protease, Ubl conjugation pathway, Isopeptide bond, Nucleus, Phosphoprotein, Ubl conjugation, hydrolase-hydrolase inhibitor COMPLEX
Deposited on
2009-07-26, released
2010-06-16
The last revision prior to the SCOPe 2.03 freeze date was dated
2010-06-16, with a file datestamp of
2010-06-11.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.211
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin carboxyl-terminal hydrolase isozyme L1
Species: Homo sapiens [TaxId:9606]
Gene: PGP9.5, UCHL1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3ifwa_ - Chain 'B':
Compound: Ubiquitin
Species: Homo sapiens [TaxId:9606]
Gene: RPS27A, UBA52, UBA80, UBB, UBC, UBCEP1, UBCEP2, UBIQ_HUMAN
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3ifwb_ - Heterogens: GVE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ifwA (A:)
gplgsmqlkpmeinpemlnkvlyrlgvagqwrfvdvlgleeeslgsvpapacallllfpl
taqhenfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlk
qflsetekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyel
dgrmpfpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
Sequence, based on observed residues (ATOM records): (download)
>3ifwA (A:)
mqlkpmeinpemlnkvlyrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
nfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlkqflse
tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3ifwB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrg