PDB entry 3id8

View 3id8 on RCSB PDB site
Description: Ternary complex of human pancreatic glucokinase crystallized with activator, glucose and AMP-PNP
Class: transferase
Keywords: Glucokinase, Hexokinase IV, ATP-binding, Diabetes mellitus, Disease mutation, Glycolysis, Kinase, Nucleotide-binding, Transferase
Deposited on 2009-07-20, released 2010-07-28
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-04-25, with a file datestamp of 2012-04-20.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.205
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35557 (16-End)
      • expression tag (9-15)
    Domains in SCOPe 2.03: d3id8a1, d3id8a2
  • Heterogens: GLC, MRK, ANP, MG, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3id8A (A:)
mghhhhhhenlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasv
kmlptyvrstpegsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedam
tgtaemlfdyisecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasg
aegnnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacym
eemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekligg
kymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstl
glrpsttdcdivrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvykl
hpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3id8A (A:)
nlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrs
tpegsevgdflsldlggtnfrvmlvkvgegqwsvktkhqmysipedamtgtaemlfdyis
ecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrd
aikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegd
egrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvll
rlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdiv
rracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasv
rrltpsceitfieseegsgrgaalvsavac