PDB entry 3i8a
View 3i8a on RCSB PDB site
Description: Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and 2,4-diamino-5-(3-(2,5-dimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120B)
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: NADPH, One-carbon metabolism, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2009-07-09, released
2010-02-09
The last revision prior to the SCOPe 2.07 freeze date was dated
2013-11-20, with a file datestamp of
2013-11-15.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: 0.208
AEROSPACI score: 0.26
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'X':
Compound: dihydrofolate reductase
Species: Staphylococcus aureus [TaxId:1280]
Gene: dfrB, folA
Database cross-references and differences (RAF-indexed):
- Uniprot P0A017 (0-156)
- engineered (29)
- engineered (97)
Domains in SCOPe 2.07: d3i8ax_ - Heterogens: N22, NDP, HOH