PDB entry 3i6k

View 3i6k on RCSB PDB site
Description: Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201
Class: Immune System
Keywords: HLA-A2, SARS-CoV, Membrane glycoprotein, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, Envelope protein, Golgi apparatus, Viral matrix protein, Virion, Immune System
Deposited on 2009-07-07, released 2010-06-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2010-11-03, with a file datestamp of 2010-10-29.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLA-A*0201 allele, HLAA, Homo sapiens MHC class I antigen (HLA-A)
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, beta-2-microglobulin, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3i6kb_
  • Chain 'C':
    Compound: Membrane glycoprotein peptide
    Species: SARS coronavirus TJF, synthetic [TaxId:284672]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLA-A*0201 allele, HLAA, Homo sapiens MHC class I antigen (HLA-A)
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, beta-2-microglobulin, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.03: d3i6kf_
  • Chain 'G':
    Compound: Membrane glycoprotein peptide
    Species: SARS coronavirus TJF, synthetic [TaxId:284672]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3i6kB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3i6kF (F:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'G':
    No sequence available.