PDB entry 3i4a

View 3i4a on RCSB PDB site
Description: Crystal structure of dimethylarginine dimethylaminohydrolase-1 (DDAH-1) in complex with N5-(1-iminopropyl)-L-ornithine
Class: hydrolase
Keywords: DDAH, HYDROLASE, NITRIC OXIDE SYNTHASE REGULATION, Acetylation, Metal-binding, Zinc
Deposited on 2009-07-01, released 2009-08-25
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-10-06, with a file datestamp of 2009-10-02.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.178
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DDAH, DDAH1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3i4aa_
  • Chain 'B':
    Compound: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DDAH, DDAH1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3i4ab_
  • Heterogens: LN5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3i4aA (A:)
mgsshhhhhhssglvprgshmasmaglghpaafgrathavvralpeslgqhalrsakgee
vdvaraerqhqlyvgvlgsklglqvvelpadeslpdcvfvedvavvceetalitrpgaps
rrkevdmmkealeklqlnivemkdenatldggdvlftgreffvglskrtnqrgaeiladt
fkdyavstvpvadglhlksfcsmagpnliaigssesaqkalkimqqmsdhrydkltvpdd
iaanciylnipnkghvllhrtpeeypesakvyeklkdhmlipvsmselekvdglltccsv
linkkvds

    Sequence, based on observed residues (ATOM records): (download) 
    >3i4aA (A:)
aafgrathavvralpeslgqhalrsakgeevdvaraerqhqlyvgvlgsklglqvvelpa
deslpdcvfvedvavvceetalitrpgapsrrkevdmmkealeklqlnivemkdenatld
ggdvlftgreffvglskrtnqrgaeiladtfkdyavstvpvadglhlksfcsmagpnlia
igssesaqkalkimqqmsdhrydkltvpddiaanciylnipnkghvllhrtpeeypesak
vyeklkdhmlipvsmselekvdglltccsvlinkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3i4aB (B:)
mgsshhhhhhssglvprgshmasmaglghpaafgrathavvralpeslgqhalrsakgee
vdvaraerqhqlyvgvlgsklglqvvelpadeslpdcvfvedvavvceetalitrpgaps
rrkevdmmkealeklqlnivemkdenatldggdvlftgreffvglskrtnqrgaeiladt
fkdyavstvpvadglhlksfcsmagpnliaigssesaqkalkimqqmsdhrydkltvpdd
iaanciylnipnkghvllhrtpeeypesakvyeklkdhmlipvsmselekvdglltccsv
linkkvds

    Sequence, based on observed residues (ATOM records): (download) 
    >3i4aB (B:)
aafgrathavvralpeslgqhalrsakgeevdvaraerqhqlyvgvlgsklglqvvelpa
deslpdcvfvedvavvceetalitrpgapsrrkevdmmkealeklqlnivemkdenatld
ggdvlftgreffvglskrtnqrgaeiladtfkdyavstvpvadglhlksfcsmagpnlia
igssesaqkalkimqqmsdhrydkltvpddiaanciylnipnkghvllhrtpeeypesak
vyeklkdhmlipvsmselekvdglltccsvlinkk