PDB entry 3i3r

View 3i3r on RCSB PDB site
Description: X-ray structure dihydrofolate reductase/thymidylate synthase from babesia bovis at 2.35A resolution
Class: transferase
Keywords: SSGCID, babesia bovis, dihydrofolate reductase, thymidylate synthase, Methyltransferase, Transferase, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease
Deposited on 2009-06-30, released 2009-08-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydrofolate reductase/thymidylate synthase
    Species: Babesia bovis [TaxId:484906]
    Gene: BBOV_II000780
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i3ra1, d3i3ra2
  • Chain 'B':
    Compound: Dihydrofolate reductase/thymidylate synthase
    Species: Babesia bovis [TaxId:484906]
    Gene: BBOV_II000780
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i3rb1, d3i3rb2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3i3rA (A:)
msnsyegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiq
nvvifgrktyesipkaslplknrinvilsrtvkevpgclvyedlstairdlranvphnki
filggsflykevldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsyd
fviyerkdcktvfpdppfdqllmtgtdisvpkpkyvacpgvrirnheefqyldiladvls
hgvlkpnrtgtdayskfgyqmrfdlsrsfpllttkkvalrsiieellwfikgstngndll
aknvriwelngrrdfldkngftdreehdlgpiygfqwrhfgaeyldmhadytgkgidqla
eiinriktnpndrrlivcswnvsdlkkmalppchcffqfyvsdnklscmmhqrscdlglg
vpfniasysiltamvaqvcglglgefvhnladahiyvdhvdavttqiariphpfprlrln
pdirniedftiddivvedyvshppipmamsa

    Sequence, based on observed residues (ATOM records): (download) 
    >3i3rA (A:)
yegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiqnvvi
fgrktyeplknrinvilsrtvkevpgclvyedlstairdlranvphnkifilggsflyke
vldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsydfviyerkppfd
qllmtgtdiskpkyvacpgvrirnheefqyldiladvlshgvlkpnrtgtdayskfgyqm
rfdlsrsfpllttkkvalrsiieellwfikgstngndllaknvriwelngrrdfldkngf
tdreehdlgpiygfqwrhfgaeyldmhadytgkgidqlaeiinriktnpndrrlivcswn
vsdlkkmalppchcffqfyvsdnklscmmhqrscdlglgvpfniasysiltamvaqvcgl
glgefvhnladahiyvdhvdavttqiariphpfprlrlnpdirniedftiddivvedyvs
hppipmams

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3i3rB (B:)
msnsyegcgdltifvavalnkvighknqipwphithdfrflrngttyippevlsknpdiq
nvvifgrktyesipkaslplknrinvilsrtvkevpgclvyedlstairdlranvphnki
filggsflykevldnglcdkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsyd
fviyerkdcktvfpdppfdqllmtgtdisvpkpkyvacpgvrirnheefqyldiladvls
hgvlkpnrtgtdayskfgyqmrfdlsrsfpllttkkvalrsiieellwfikgstngndll
aknvriwelngrrdfldkngftdreehdlgpiygfqwrhfgaeyldmhadytgkgidqla
eiinriktnpndrrlivcswnvsdlkkmalppchcffqfyvsdnklscmmhqrscdlglg
vpfniasysiltamvaqvcglglgefvhnladahiyvdhvdavttqiariphpfprlrln
pdirniedftiddivvedyvshppipmamsa

    Sequence, based on observed residues (ATOM records): (download) 
    >3i3rB (B:)
yegcgdltifvavalnkvighknqipwphithdfrflrngttyipppdiqnvvifgrkty
elknrinvilsrtvkevpgclvyedlstairdlranvphnkifilggsflykevldnglc
dkiyltrlnkeypgdtyfpdipdtfeitaisptfstdfvsydfviyerkppfdqllmtgt
diskpkyvacpgvrirnheefqyldiladvlshgvlkpnrtgtdayskfgyqmrfdlsrs
fpllttkkvalrsiieellwfikgstngndllaknvriwelngrrdfldkngftdreehd
lgpiygfqwrhfgaeyldmhadytgkgidqlaeiinriktnpndrrlivcswnvsdlkkm
alppchcffqfyvsdnklscmmhqrscdlglgvpfniasysiltamvaqvcglglgefvh
nladahiyvdhvdavttqiariphpfprlrlnpdirniedftiddivvedyvshppi