PDB entry 3i2b

View 3i2b on RCSB PDB site
Description: The crystal structure of human 6 Pyruvoyl Tetrahydrobiopterin Synthase
Class: lyase
Keywords: 6 pyruvoyl tetrahydrobiopterin synthase, PTS, PTP synthase, Structural Genomics, Structural Genomics Consortium, SGC, Disease mutation, Lyase, Metal-binding, Phenylketonuria, Phosphoprotein, Tetrahydrobiopterin biosynthesis
Deposited on 2009-06-29, released 2009-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2ba_
  • Chain 'B':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bb_
  • Chain 'C':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bc_
  • Chain 'D':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bd_
  • Chain 'E':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2be_
  • Chain 'F':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bf_
  • Chain 'G':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bg_
  • Chain 'H':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bh_
  • Chain 'I':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bi_
  • Chain 'J':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bj_
  • Chain 'K':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bk_
  • Chain 'L':
    Compound: 6-pyruvoyl tetrahydrobiopterin synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3i2bl_
  • Heterogens: EDO, NI, MG, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3i2bA (A:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bA (A:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3i2bB (B:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bB (B:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3i2bC (C:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bC (C:)
rcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpatg
mvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvly
kvkvyetdnnivvykge

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3i2bD (D:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bD (D:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3i2bE (E:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bE (E:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3i2bF (F:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bF (F:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3i2bG (G:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bG (G:)
cqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpatgm
vmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvlyk
vkvyetdnnivvykge

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3i2bH (H:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bH (H:)
rcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpatg
mvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvly
kvkvyetdnnivvykge

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3i2bI (I:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bI (I:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3i2bJ (J:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bJ (J:)
rcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpatg
mvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvly
kvkvyetdnnivvykge

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >3i2bK (K:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bK (K:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3i2bL (L:)
smgrrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeid
patgmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpv
gvlykvkvyetdnnivvykge

    Sequence, based on observed residues (ATOM records): (download) 
    >3i2bL (L:)
rrcqaqvsrrisfsashrlyskflsdeenlklfgkcnnpnghghnykvvvtvhgeidpat
gmvmnladlkkymeeaimqpldhknldmdvpyfadvvsttenvavyiwdnlqkvlpvgvl
ykvkvyetdnnivvykge