PDB entry 3i0a

View 3i0a on RCSB PDB site
Description: Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin
Class: antimicrobial protein
Keywords: NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid, Secreted, ANTIMICROBIAL PROTEIN
Deposited on 2009-06-24, released 2010-06-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: HNL, LCN2, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-197)
      • engineered (106)
      • engineered (153)
    Domains in SCOPe 2.08: d3i0aa_
  • Chain 'B':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: HNL, LCN2, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered (106)
      • engineered (153)
    Domains in SCOPe 2.08: d3i0ab_
  • Chain 'C':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: HNL, LCN2, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-197)
      • engineered (106)
      • engineered (153)
    Domains in SCOPe 2.08: d3i0ac_
  • Heterogens: SO4, FE, 3ET, 2DS, DBH, GOL, MCJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3i0aA (A:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsylvrvvstnynqhamvffkkvsqnreyfaitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3i0aA (A:)
sdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedksy
nvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvffk
kvsqnreyfaitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3i0aB (B:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsylvrvvstnynqhamvffkkvsqnreyfaitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3i0aB (B:)
dlipapplskvplqqnfqdnqfqgkwyvvglagnailrkmyatiyelkdksynvtsvlfr
kkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvffkkvsqnrey
faitlygrtkeltslkenfirfskslglpenhivfpvpidqcid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3i0aC (C:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsylvrvvstnynqhamvffkkvsqnreyfaitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3i0aC (C:)
stsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedk
synvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvf
fkkvsqnreyfaitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg