PDB entry 3hy2

View 3hy2 on RCSB PDB site
Description: Crystal Structure of Sulfiredoxin in Complex with Peroxiredoxin I and ATP:Mg2+
Class: oxidoreductase
Keywords: protein-protein Complex, redox biology, protein repair, sulfur chemistry, Antioxidant, Disulfide bond, Oxidoreductase, Peroxidase, Phosphoprotein, Redox-active center, ATP-binding, Magnesium, Nucleotide-binding
Deposited on 2009-06-22, released 2009-10-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-09-18, with a file datestamp of 2013-09-13.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.226
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX1, PAGA, PAGB, TDPX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06830
      • engineered (51)
      • engineered (70)
      • engineered (82)
      • engineered (85)
      • engineered (172)
      • engineered (184)
    Domains in SCOPe 2.07: d3hy2a_
  • Chain 'B':
    Compound: Peroxiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX1, PAGA, PAGB, TDPX2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06830
      • engineered (51)
      • engineered (70)
      • engineered (82)
      • engineered (85)
      • engineered (172)
      • engineered (184)
    Domains in SCOPe 2.07: d3hy2b_
  • Chain 'X':
    Compound: Sulfiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: C20orf139, SRX, SRXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BYN0 (Start-109)
      • engineered (15)
      • engineered (71)
    Domains in SCOPe 2.07: d3hy2x_
  • Chain 'Y':
    Compound: Sulfiredoxin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: C20orf139, SRX, SRXN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BYN0 (Start-109)
      • engineered (15)
      • engineered (71)
    Domains in SCOPe 2.07: d3hy2y_
  • Heterogens: MG, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hy2A (A:)
mssgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvdpteiiafs
draeefkklnsqvigasvdshfehlewvntpkkqgglgpmniplvsdpkrtiaqdygvlk
adegisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpg
sdticpdvqkskeyfskqkghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hy2A (A:)
sgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvdpteiiafsdr
aeefkklnsqvigasvdshfehlewvntpkkqgglgpmniplvsdpkrtiaqdygvlkad
egisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpgsd
ticpd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hy2B (B:)
mssgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvdpteiiafs
draeefkklnsqvigasvdshfehlewvntpkkqgglgpmniplvsdpkrtiaqdygvlk
adegisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpg
sdticpdvqkskeyfskqkghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hy2B (B:)
sgnakighpapnfkatavmpdgqfkdislsdykgkyvvfffypldftfvdpteiiafsdr
aeefkklnsqvigasvdshfehlewvntpkkqgglgpmniplvsdpkrtiaqdygvlkad
egisfrglfiiddkgilrqitvndlpvgrsvdetlrlvqafqftdkhgevspagwkpgsd
ticp

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >3hy2X (X:)
ghpmsihsgriaavhcvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikga
qggdyfysfggahryaayqqlqretipaklvqstlsdlrvylgastpdlq

    Sequence, based on observed residues (ATOM records): (download) 
    >3hy2X (X:)
riaavhcvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikgaqggdyfysf
ggahryaayqqlqretipaklvqstlsdlrvylgastpdlq

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >3hy2Y (Y:)
ghpmsihsgriaavhcvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikga
qggdyfysfggahryaayqqlqretipaklvqstlsdlrvylgastpdlq

    Sequence, based on observed residues (ATOM records): (download) 
    >3hy2Y (Y:)
riaavhcvplsvlirplpsvldpakvqslvdtiredpdsvppidvlwikgaqggdyfysf
ggahryaayqqlqretipaklvqstlsdlrvylgastpdlq