PDB entry 3hxg

View 3hxg on RCSB PDB site
Description: Crystal structure of Schistsome eIF4E complexed with m7GpppA and 4E-BP
Class: translation
Keywords: protein-mRNA cap complex, Acetylation, Phosphoprotein, Protein synthesis inhibitor, Translation regulation
Deposited on 2009-06-20, released 2009-08-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-11-10, with a file datestamp of 2009-11-06.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.215
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: eukaryotic translation initiation factor 4e
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: eif4e
    Database cross-references and differences (RAF-indexed):
    • PDB 3HXG (Start-188)
    Domains in SCOPe 2.08: d3hxga1, d3hxga2
  • Chain 'C':
    Compound: eukaryotic translation initiation factor 4e-binding protein 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13541 (4-End)
      • insertion (3)
  • Heterogens: GTA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hxgA (A:)
gplgspefphplqdswsyylfqfrkaldwdeclekvatfstiedfwsvlthtvrpreity
gkdlymfksdimpkwedpknenggrwlinvtarqdvdflwdellmlligsdwdtdeedrq
icgavfqprsrgsklsvwltsdneeetilsigrrikerleledtiyfqpvsdqrsqtrgs
dictgkyei

    Sequence, based on observed residues (ATOM records): (download) 
    >3hxgA (A:)
efphplqdswsyylfqfrkaldwdeclekvatfstiedfwsvlthtvrpreitygkdlym
fksdimpkwedpknenggrwlinvtarqdvdflwdellmlligsdwdtdeedrqicgavf
qprsrgsklsvwltsdneeetilsigrrikerleledtiyfqpvsdqrsqtrgsdictgk
yei

  • Chain 'C':
    No sequence available.