PDB entry 3hwk

View 3hwk on RCSB PDB site
Description: crystal structure of methylcitrate synthase from mycobacterium tuberculosis
Deposited on 2009-06-17, released 2009-06-30
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Methylcitrate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: gltA1, gltA-3, MT1163, Rv1131
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SIN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hwkA (A:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkA (A:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlpgt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hwkB (B:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkB (B:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3hwkC (C:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkC (C:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3hwkD (D:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkD (D:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlpg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3hwkE (E:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkE (E:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlpgtf

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3hwkF (F:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkF (F:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlpg

  • Chain 'G':
    Sequence, based on SEQRES records:
    >3hwkG (G:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkG (G:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlp

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3hwkH (H:)
mahhhhhhmgtleaqtqgpgsmtgplaaarsvaatksmtaptvderpdikkglagvvvdt
taiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdaelalfsqrerasrrv
drsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamrmmavlptivaidm
rrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyaehgfnastfaarvv
tstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewlraklarkekimgf
ghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatgilpnldfptgpay
ylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheqrvlpgtf

    Sequence, based on observed residues (ATOM records):
    >3hwkH (H:)
dikkglagvvvdttaiskvvpqtnsltyrgypvqdlaarcsfeqvafllwrgelptdael
alfsqrerasrrvdrsmlsllaklpdnchpmdvvrtaisylgaedpdeddaaanrakamr
mmavlptivaidmrrrrglppiaphsglgyaqnflhmcfgevpetavvsafeqsmilyae
hgfnastfaarvvtstqsdiysavtgaigalkgrlhgganeavmhdmieigdpanarewl
raklarkekimgfghrvyrhgdsrvptmkralervgtvrdgqrwldiyqvlaaemasatg
ilpnldfptgpayylmgfdiasftpifvmsritgwtahimeqatanalirplsaycgheq
rvlpg