PDB entry 3hwg

View 3hwg on RCSB PDB site
Description: Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with Fe-TrenCam-hopo2
Class: transport protein
Keywords: Lipocalin, siderophore, beta-barrel, Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid, Secreted, TRANSPORT PROTEIN
Deposited on 2009-06-17, released 2010-06-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: HNL, LCN2, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188 (Start-197)
      • engineered (106)
    Domains in SCOPe 2.08: d3hwga_
  • Chain 'B':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: HNL, LCN2, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered (106)
    Domains in SCOPe 2.08: d3hwgb_
  • Chain 'C':
    Compound: Neutrophil gelatinase-associated lipocalin
    Species: Homo sapiens [TaxId:9606]
    Gene: HNL, LCN2, NGAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80188
      • engineered (106)
    Domains in SCOPe 2.08: d3hwgc_
  • Heterogens: FE, QED, GOL, NA, SO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hwgA (A:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsylvrvvstnynqhamvffkkvsqnreyfkitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3hwgA (A:)
tsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedks
ynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvff
kkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcidg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hwgB (B:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsylvrvvstnynqhamvffkkvsqnreyfkitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3hwgB (B:)
sdlipapplskvplqqnfqdnqfqgkwyvvglagnailrdpqkmyatiyelkksynvtsv
lfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvffkkvsqn
reyfkitlygrtkeltslkenfirfskslglpenhivfpvpidqcid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hwgC (C:)
mplgllwlglallgalhaqaqdstsdlipapplskvplqqnfqdnqfqgkwyvvglagna
ilredkdpqkmyatiyelkedksynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksy
pgltsylvrvvstnynqhamvffkkvsqnreyfkitlygrtkeltselkenfirfskslg
lpenhivfpvpidqcidg

    Sequence, based on observed residues (ATOM records): (download) 
    >3hwgC (C:)
tsdlipapplskvplqqnfqdnqfqgkwyvvglagnailredkdpqkmyatiyelkedks
ynvtsvlfrkkkcdywirtfvpgsqpgeftlgniksypgltsylvrvvstnynqhamvff
kkvsqnreyfkitlygrtkeltselkenfirfskslglpenhivfpvpidqcid