PDB entry 3hvq

View 3hvq on RCSB PDB site
Description: Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Neurabin
Class: hydrolase/hydrolase regulator
Keywords: PP1, NEURABIN, SERINE/THREONINE PHOSPHATASE, POST SYNAPTIC DENSITY, GLUTAMETERGIC RECEPTORS, CARBOHYDRATE METABOLISM, CELL CYCLE, CELL DIVISION, GLYCOGEN METABOLISM, HYDROLASE, IRON, MANGANESE, METAL-BINDING, PHOSPHOPROTEIN, PROTEIN PHOSPHATASE, ACTIN-BINDING, CELL JUNCTION, CELL PROJECTION, CYTOSKELETON, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, NEUROGENESIS, NUCLEUS, SYNAPSE, Synaptosome, HYDROLASE-HYDROLASE REGULATOR COMPLEX
Deposited on 2009-06-16, released 2010-03-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.164
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1A, PPP1CA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hvqa_
  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1A, PPP1CA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3hvqb_
  • Chain 'C':
    Compound: Neurabin-1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ppp1r9a
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Neurabin-1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ppp1r9a
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MN, PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hvqA (A:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpadk
nkgkygqfsglnpggrpitpprnsakakk

    Sequence, based on observed residues (ATOM records): (download) 
    >3hvqA (A:)
lnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hvqB (B:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpadk
nkgkygqfsglnpggrpitpprnsakakk

    Sequence, based on observed residues (ATOM records): (download) 
    >3hvqB (B:)
lnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.