PDB entry 3hu2

View 3hu2 on RCSB PDB site
Description: Structure of p97 N-D1 R86A mutant in complex with ATPgS
Class: transport protein
Keywords: p97, VCP, TRANSPORT PROTEIN
Deposited on 2009-06-12, released 2010-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (85)
    Domains in SCOPe 2.08: d3hu2a1, d3hu2a2, d3hu2a3
  • Chain 'B':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (85)
    Domains in SCOPe 2.08: d3hu2b1, d3hu2b2, d3hu2b3
  • Chain 'C':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (85)
    Domains in SCOPe 2.08: d3hu2c1, d3hu2c2, d3hu2c3
  • Chain 'D':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (85)
    Domains in SCOPe 2.08: d3hu2d1, d3hu2d2, d3hu2d3
  • Chain 'E':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (85)
    Domains in SCOPe 2.08: d3hu2e1, d3hu2e2, d3hu2e3
  • Chain 'F':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (85)
    Domains in SCOPe 2.08: d3hu2f1, d3hu2f2, d3hu2f3
  • Heterogens: AGS, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hu2A (A:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu2A (A:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnpsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hu2B (B:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu2B (B:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnpsa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hu2C (C:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu2C (C:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnpsa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hu2D (D:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu2D (D:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnpsa

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3hu2E (E:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu2E (E:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnpsa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3hu2F (F:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu2F (F:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnavvrnnlrvrlgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnpsa