PDB entry 3hu1

View 3hu1 on RCSB PDB site
Description: Structure of p97 N-D1 R95G mutant in complex with ATPgS
Class: transport protein
Keywords: p97, VCP, TRANSPORT PROTEIN
Deposited on 2009-06-12, released 2010-06-16
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-02-15, with a file datestamp of 2012-02-10.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: 0.241
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (94)
    Domains in SCOPe 2.05: d3hu1a1, d3hu1a2, d3hu1a3
  • Chain 'B':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (94)
    Domains in SCOPe 2.05: d3hu1b1, d3hu1b2, d3hu1b3
  • Chain 'C':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (94)
    Domains in SCOPe 2.05: d3hu1c1, d3hu1c2, d3hu1c3
  • Chain 'D':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (94)
    Domains in SCOPe 2.05: d3hu1d1, d3hu1d2, d3hu1d3
  • Chain 'E':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (94)
    Domains in SCOPe 2.05: d3hu1e1, d3hu1e2, d3hu1e3
  • Chain 'F':
    Compound: Transitional endoplasmic reticulum ATPase
    Species: Homo sapiens [TaxId:9606]
    Gene: P97, VCP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P55072
      • engineered mutation (94)
    Domains in SCOPe 2.05: d3hu1f1, d3hu1f2, d3hu1f3
  • Heterogens: AGS, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hu1A (A:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu1A (A:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hu1B (B:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu1B (B:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hu1C (C:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu1C (C:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hu1D (D:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu1D (D:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3hu1E (E:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu1E (E:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3hu1F (F:)
masgadskgddlstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllk
gkkrreavcivlsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpid
dtvegitgnlfevylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdt
vihcegepikredeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprg
illygppgtgktliaravanetgaffflingpeimsklagesesnlrkafeeaeknapai
ifideldaiapkrekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrf
grfdrevdigipdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaal
qairkkmdlidledetidaevmnslavtmddfrwalsqsnpsalretvvevpqvtwedig
grshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3hu1F (F:)
lstailkqknrpnrlivdeainednsvvslsqpkmdelqlfrgdtvllkgkkrreavciv
lsddtcsdekirmnrvvrnnlrvglgdvisiqpcpdvkygkrihvlpiddtvegitgnlf
evylkpyfleayrpirkgdiflvrggmravefkvvetdpspycivapdtvihcegepikr
edeeeslnevgyddiggcrkqlaqikemvelplrhpalfkaigvkpprgillygppgtgk
tliaravanetgaffflingpeimsklagesesnlrkafeeaeknapaiifideldaiap
krekthgeverrivsqlltlmdglkqrahvivmaatnrpnsidpalrrfgrfdrevdigi
pdatgrleilqihtknmkladdvdleqvanethghvgadlaalcseaalqairkkmdlid
ledetidaevmnslavtmddfrwalsqsnps