PDB entry 3hsv
View 3hsv on RCSB PDB site
Description: Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2
Class: protein binding, ligase
Keywords: ubiquitin, E3, SPOP, MacroH2A, Nucleus, Ubl conjugation pathway, Alternative splicing, Chromatin regulator, Chromosomal protein, DNA-binding, Isopeptide bond, Methylation, Nucleosome core, Phosphoprotein, Ubl conjugation, ligase, protein binding
Deposited on
2009-06-10, released
2009-10-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-02-19, with a file datestamp of
2020-02-14.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Speckle-type POZ protein
Species: Homo sapiens [TaxId:9606]
Gene: SPOP
Database cross-references and differences (RAF-indexed):
- Uniprot O43791 (6-End)
- engineered mutation (118)
Domains in SCOPe 2.08: d3hsva_ - Chain 'B':
Compound: Speckle-type POZ protein
Species: Homo sapiens [TaxId:9606]
Gene: SPOP
Database cross-references and differences (RAF-indexed):
- Uniprot O43791 (6-End)
- engineered mutation (118)
Domains in SCOPe 2.08: d3hsvb_ - Chain 'M':
Compound: Core histone macro-H2A.1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: ZN, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3hsvA (A:)
gsggsgkvvkfsymwtinnfsfcreemgeviksstfssgandklkwclrvnpkgldeesk
dylslylllvscpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgf
lldeangllpddkltlfcevsvvqd
Sequence, based on observed residues (ATOM records): (download)
>3hsvA (A:)
kvvkfsymwtinnfsfcreemgeviksstfsslkwclrvnpkgldeeskdylslylllvs
cpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgflldeangllpd
dkltlfcevsvvq
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3hsvB (B:)
gsggsgkvvkfsymwtinnfsfcreemgeviksstfssgandklkwclrvnpkgldeesk
dylslylllvscpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgf
lldeangllpddkltlfcevsvvqd
Sequence, based on observed residues (ATOM records): (download)
>3hsvB (B:)
kvvkfsymwtinnfsfcreemgeviksstfsslkwclrvnpkgldeeskdylslylllvs
cpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgflldeangllpd
dkltlfcevsvv
- Chain 'M':
No sequence available.