PDB entry 3hs5

View 3hs5 on RCSB PDB site
Description: x-ray crystal structure of arachidonic acid bound to the cyclooxygenase channel of cyclooxygenase-2
Deposited on 2009-06-10, released 2010-05-12
The last revision was dated 2021-10-13, with a file datestamp of 2021-10-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin G/H synthase 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05769 (6-590)
      • expression tag (0-5)
      • engineered mutation (566)
  • Chain 'B':
    Compound: Prostaglandin G/H synthase 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05769 (6-590)
      • expression tag (0-5)
      • engineered mutation (566)
  • Heterogens: ACD, AKR, COH, NAG, BOG, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hs5A (A:)
hhhhhhpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpnt
vhyilthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsy
ytralppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfth
qffktdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvk
dtqvemiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeq
lfqtsrliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhw
hpllpdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqav
akasidqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypal
lvekprpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqsl
icnnvkgcpftsfnvqdpqptktatiaasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records):
    >3hs5A (A:)
hhpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeqlfqt
srliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hs5B (B:)
hhhhhhpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpnt
vhyilthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsy
ytralppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfth
qffktdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvk
dtqvemiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeq
lfqtsrliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhw
hpllpdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqav
akasidqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypal
lvekprpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqsl
icnnvkgcpftsfnvqdpqptktatiaasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records):
    >3hs5B (B:)
hhpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeqlfqt
srliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnv