PDB entry 3hrz

View 3hrz on RCSB PDB site
Description: cobra venom factor (cvf) in complex with human factor b
Deposited on 2009-06-10, released 2009-07-07
The last revision was dated 2021-10-13, with a file datestamp of 2021-10-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cobra venom factor
    Species: Naja kaouthia [TaxId:8649]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Cobra venom factor
    Species: Naja kaouthia [TaxId:8649]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Cobra venom factor
    Species: Naja kaouthia [TaxId:8649]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: complement factor b
    Species: Homo sapiens [TaxId:9606]
    Gene: CFB, BF, BFD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00751 (0-738)
      • engineered mutation (253)
      • engineered mutation (259)
      • insertion (739-740)
  • Heterogens: NAG, MG, K, P6G, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hrzA (A:)
alytlitpavlrtdteeqilveahgdstpkqldifvhdfprkqktlfqtrvdmnpaggml
vtptieipakevstdsrqnqyvvvqvtgpqvrlekvvllsyqssflfiqtdkgiytpgsp
vlyrvfsmdhntskmnktvivefqtpegilvssnsvdlnffwpynlpdlvslgtwrivak
yehspenytayfdvrkyvlpsfevrlqpsekffyidgnenfhvsitarylygeevegvaf
vlfgvkiddakksipdsltripiidgdgkatlkrdtfrsrfpnlnelvghtlyasvtvmt
esgsdmvvteqsgihivaspyqihftktpkyfkpgmpyeltvyvtnpdgspaahvpvvse
afhsmgttlsdgtaklilniplnaqslpitvrtnhgdlprerqatksmtaiayqtqggsg
nylhvaitsteikpgdnlpvnfnvkgnanslkqikyftylilnkgkifkvgrqprrdgqn
lvtmnlhitpdlipsfrfvayyqvgnneivadsvwvdvkdtcmgtlvvkgdnliqmpgaa
mkiklegdpgarvglvavdkavyvlndkykisqakiwdtieksdfgctagsgqnnlgvfe
daglalttstnlntkqrsaakcpqpan

    Sequence, based on observed residues (ATOM records):
    >3hrzA (A:)
alytlitpavlrtdteeqilveahgdstpkqldifvhdfprkqktlfqtrvdmnpaggml
vtptieipakevstdnqyvvvqvtgpqvrlekvvllsyqssflfiqtdkgiytpgspvly
rvfsmdhtvivefqtpegilvssnsvdlnffwpynlpdlvslgtwrivakyehspenyta
yfdvrkyvlpsfevrlqpsekffyidgnenfhvsitarylygeevegvafvlfgvkidda
kksipdsltripiidgdgkatlkrdtfrsrfpnlnelvghtlyasvtvmtesgsdmvvte
qsgihivaspyqihftktpkyfkpgmpyeltvyvtnpdgspaahvpvvseafhsmgttls
dgtaklilniplnaqslpitvrtnhgdlprerqatksmtaiayqtqggsgnylhvaitst
eikpgdnlpvnfnvkgnanslkqikyftylilnkgkifkvgrqprrdgqnlvtmnlhitp
dlipsfrfvayyqvgnneivadsvwvdvkdtcmgtlvvkgdnliqmpgaamkiklegdpg
arvglvavdkavyvlndkykisqakiwdtieksdfgctagsgqnnlgvfedaglalttst
nlntkqrsaakcpq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hrzB (B:)
ddnedgfiadsdiisrsdfpkswlwltkdlteepnsqgissktmsfylrdsittwvvlav
sftptkgicvaepyeirvmkvffidlqmpysvvkneqveirailhnyvnediyvrvelly
npafcsastkgqryrqqfpikalssravpfvivpleqglhdveikasvqealwsdgvrkk
lkvvpegvqksivtivkldprakgvggtqlevikarklddrvpdteietkiiiqgdpvaq
iiensidgskln

    Sequence, based on observed residues (ATOM records):
    >3hrzB (B:)
dgfiadsdiisrsdfpkswlwltkdlteepnsqgissktmsfylrdsittwvvlavsftp
tkgicvaepyeirvmkvffidlqmpysvvkneqveirailhnyvnediyvrvellynpaf
csastkgqryrqqfpikalssravpfvivpleqglhdveikasvqealwsdgvrkklkvv
pegvqksivtivkldprakgvggtqlevikarklddrvpdteietkiiiqgdp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3hrzC (C:)
eiqmpthkdlnlditielpdrevpiryrinyenallartvetklnqditvtasgdgkatm
tiltfynaqlqekanvcnkfhlnvsvenihlnamgakgalmlkictrylgevdstmtiid
ismltgflpdaedltrlskgvdryisryevdnnmaqkvaviiylnkvshsedeclhfkil
khfevgfiqpgsvkvysyynldekctkfyhpdkgtgllnkicignvcrcagetcsslnhq
eridvplqiekacetnvdyvyktkllrieeqdgndiyvmdvlevikqgtdenprakthqy
isqrkcqealnlkvnddyliwgsrsdllptkdkisyiitkntwierwphedecqeeefqk
lcddfaqfsytltefgcpt

    Sequence, based on observed residues (ATOM records):
    >3hrzC (C:)
dlnlditielpdrevpiryrinyenallartvetklnqditvtasgdgkatmtiltfyna
qlvcnkfhlnvsvenihlnkgalmlkictrylgevdstmtiidismltgflpdaedltrl
skgvdryisryevdnnmaqkvaviiylnkvshsedeclhfkilkhfevgfiqpgsvkvys
yynldekctkfyhpdkgtgllnkicignvcrcagetcsslnhqeridvplqiekacetnv
dyvyktkllrieeqdgndiyvmdvlevikqgtdenprakthqyisqrkcqealnlkvndd
yliwgsrsdllptkdkisyiitkntwierwphedecqeeefqklcddfaqfsytltefgc
pt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3hrzD (D:)
tpwslarpqgscslegveikggsfrllqegqaleyvcpsgfypypvqtrtcrstgswstl
ktqdqktvrkaecraihcprphdfengeywprspyynvsdeisfhcydgytlrgsanrtc
qvngrwsgqtaicdngagycsnpgipigtrkvgsqyrledsvtyhcsrgltlrgsqrrtc
qeggswsgtepscqdsfmydtpqevaeaflssltetiegvdaedghgpgeqqkrkivldp
sgsmniylvldgsgsigasdftgakkclvnliekvasygvkpryglvtyatypkiwvkvs
eadssnadwvtkqlneinyedhklksgtntkkalqavysmmswpddvppegwnrtrhvii
lmtdglhnmggdpitvideirdllyigkdrknpredyldvyvfgvgplvnqvninalask
kdneqhvfkvkdmenledvfyqmidesqslslcgmvwehrkgtdyhkqpwqakisvirps
kghescmgavvseyfvltaahcftvddkehsikvsvggekrdleievvlfhpnyningkk
eagipefydydvaliklknklkygqtirpiclpctegttralrlpptttcqqqkeellpa
qdikalfvseeekkltrkevyikngdkkgscerdaqyapgydkvkdisevvtprflctgg
vspyadpntcrgdsggplivhkrsrfiqvgviswgvvdvcknqkrqkqvpahardfhinl
fqvlpwlkeklqdedlgflaa

    Sequence, based on observed residues (ATOM records):
    >3hrzD (D:)
scslegveikggsfrllqegqaleyvcpsgfypypvqtrtcrstgswstlktqdqktvrk
aecraihcprphdfengeywprspyynvsdeisfhcydgytlrgsanrtcqvngrwsgqt
aicdngagycsnpgipigtrkvgsqyrledsvtyhcsrgltlrgsqrrtcqeggswsgte
pscqdsfmydtpqevaeaflssltetkrkivldpsgsmniylvldgsgsigasdftgakk
clvnliekvasygvkpryglvtyatypkiwvkvseadssnadwvtkqlneinyedhklks
gtntkkalqavysmmswpvppegwnrtrhviilmtdglhnmggdpitvideirdllyigk
drknpredyldvyvfgvgplvnqvninalaskkdneqhvfkvkdmenledvfyqmidesq
slslcgmvwehtdyhkqpwqakisvirpscmgavvseyfvltaahcfthsikvsvggekr
dleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpiclpctegttra
lrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgscerdaqyapgy
dkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgviswgvvdvck
qvpahardfhinlfqvlpwlkeklqdedlgfla