PDB entry 3hqm

View 3hqm on RCSB PDB site
Description: Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-CiSBC2
Class: protein binding, ligase
Keywords: ubiquitin, E3, SPOP, MATH, Ci, Nucleus, Ubl conjugation pathway, Developmental protein, DNA-binding, Metal-binding, Segmentation polarity protein, Zinc-finger, Protein Binding, LIGASE
Deposited on 2009-06-07, released 2009-10-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.74 Å
R-factor: 0.179
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Speckle-type POZ protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SPOP
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43791 (6-End)
      • engineered (118)
    Domains in SCOPe 2.08: d3hqma_
  • Chain 'B':
    Compound: Speckle-type POZ protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SPOP
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43791
      • engineered (118)
    Domains in SCOPe 2.08: d3hqmb_
  • Chain 'C':
    Compound: Protein cubitus interruptus
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Protein cubitus interruptus
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hqmA (A:)
gsggsgkvvkfsymwtinnfsfcreemgeviksstfssgandklkwclrvnpkgldeesk
dylslylllvscpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgf
lldeangllpddkltlfcevsvvqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3hqmA (A:)
kvvkfsymwtinnfsfcreemgeviksstfssgdklkwclrvnpkgldeeskdylslyll
lvscpsevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgflldeangll
pddkltlfcevsvvq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hqmB (B:)
gsggsgkvvkfsymwtinnfsfcreemgeviksstfssgandklkwclrvnpkgldeesk
dylslylllvscpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgf
lldeangllpddkltlfcevsvvqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3hqmB (B:)
vvkfsymwtinnfsfcreemgeviksstfssklkwclrvnpkgldeeskdylslylllvs
cpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgflldeangllpd
dkltlfcevsvv

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.