PDB entry 3hps

View 3hps on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)
Deposited on 2009-06-04, released 2010-05-19
The last revision was dated 2013-06-05, with a file datestamp of 2013-05-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.16
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-isopropylmalate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: leuA, MT3813, MTV025.058, Rv3710
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 2-isopropylmalate synthase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: leuA, MT3813, MTV025.058, Rv3710
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LEU, ZN, COI, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hpsA (A:)
mttsespdaytesfgahtivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrn
rtwpdrvidraplwcavdlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqt
dfdfvreiieqgaipddvtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvv
franraevqaiatdgarkcveqaakypgtqwrfeyspesytgteleyakqvcdavgevia
ptperpiifnlpatvemttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelg
faagadriegclfgngertgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpv
herhpyggdlvytafsgshqdainkgldamkldadaadcdvddmlwqvpylpidprdvgr
tyeavirvnsqsgkggvayimktdhglslprrlqiefsqviqkiaegtageggevspkem
wdafaeeylapvrplerirqhvdaadddggttsitatvkingveteisgsgngplaafvh
aladvgfdvavldyyehamsagddaqaaayveasvtiaspaqpgeagrhasdpvtiaspa
qpgeagrhasdpvtsktvwgvgiapsittaslravvsavnraar

    Sequence, based on observed residues (ATOM records):
    >3hpsA (A:)
tivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrnrtwpdrvidraplwcav
dlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqtdfdfvreiieqgaipdd
vtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvvfranraevqaiatdgar
kcveqaakypgtqwrfeyspesytgteleyakqvcdavgeviaptperpiifnlpatvem
ttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelgfaagadriegclfgnge
rtgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpvherhpyggdlvytafsg
shqdainkgldamkldadaadcdvddmlwqvpylpidprdvgrtyeavikggvayimktd
hglslprrlqiefsqviqkievspkemwdafaeeylapvrplerirqhvdaadddggtts
itatvkingveteisgsgngplaafvhaladvgfdvavldyyehamsagddaqaaayvea
svtiatsktvwgvgiapsittaslravvsavnraa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hpsB (B:)
mttsespdaytesfgahtivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrn
rtwpdrvidraplwcavdlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqt
dfdfvreiieqgaipddvtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvv
franraevqaiatdgarkcveqaakypgtqwrfeyspesytgteleyakqvcdavgevia
ptperpiifnlpatvemttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelg
faagadriegclfgngertgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpv
herhpyggdlvytafsgshqdainkgldamkldadaadcdvddmlwqvpylpidprdvgr
tyeavirvnsqsgkggvayimktdhglslprrlqiefsqviqkiaegtageggevspkem
wdafaeeylapvrplerirqhvdaadddggttsitatvkingveteisgsgngplaafvh
aladvgfdvavldyyehamsagddaqaaayveasvtiaspaqpgeagrhasdpvtiaspa
qpgeagrhasdpvtsktvwgvgiapsittaslravvsavnraar

    Sequence, based on observed residues (ATOM records):
    >3hpsB (B:)
tivkpagpprvgqpswnpqrassmpvnryrpfaeevepilrnrtwpdrvidraplwcavd
lrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqtdfdfvreiieqgaipddv
tiqvltqcrpeliertfqacsgapraivhfynstsilqrrvvfranraevqaiatdgark
cveqaakypgtqwrfeyspesytgteleyakqvcdavgeviaptperpiifnlpatvemt
tpnvyadsiewmsrnlanresvilslhphndrgtavaaaelgfaagadriegclfgnger
tgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpvherhpyggdlvytafsgs
hqdainkgldamkldadaadcdvddmlwqvpylpidprdvgrtyeavirvnkggvayimk
tdhglslprrlqiefsqviqkvspkemwdafaeeylapvrplerirqhvdaadddggtts
itatvkingveteisgsgngplaafvhaladvgfdvavldyyehamsagddaqaaayvea
svtiastsktvwgvgiapsittaslravvsavnraar