PDB entry 3hpj
View 3hpj on RCSB PDB site
Description: Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide
Class: immune system
Keywords: WT-1, WT1, WT126 peptide, nonapeptide, MHC class I, HLA-A2, cancer vaccine, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Phosphoprotein, Transmembrane, Disease mutation, Glycation, Immunoglobulin domain, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM
Deposited on
2009-06-04, released
2010-06-23
The last revision prior to the SCOPe 2.02 freeze date was dated
2010-08-18, with a file datestamp of
2010-08-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.184
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
- Uniprot P61769 (1-99)
- initiating methionine (0)
Domains in SCOPe 2.02: d3hpjb_ - Chain 'C':
Compound: WT126 peptide
Species: human, synthetic [TaxId:9609]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
- Uniprot P61769 (1-99)
- initiating methionine (0)
Domains in SCOPe 2.02: d3hpje_ - Chain 'F':
Compound: WT126 peptide
Species: human, synthetic [TaxId:9609]
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3hpjB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>3hpjE (E:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'F':
No sequence available.