PDB entry 3hp3

View 3hp3 on RCSB PDB site
Description: Crystal structure of CXCL12
Class: cytokine
Keywords: Chemokine, CXCL12, SDF, CYTOKINE
Deposited on 2009-06-03, released 2010-01-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.229
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3a_
  • Chain 'B':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3b_
  • Chain 'C':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3c_
  • Chain 'D':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3d_
  • Chain 'E':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3e_
  • Chain 'F':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3f_
  • Chain 'G':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3g_
  • Chain 'H':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3h_
  • Chain 'I':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3i_
  • Chain 'J':
    Compound: CXCL12 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL12, hCG_25667
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3hp3j_
  • Heterogens: AU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hp3A (A:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3A (A:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
kaln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hp3B (B:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3B (B:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
ka

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hp3C (C:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3C (C:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
kaln

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hp3D (D:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3D (D:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
kaln

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3hp3E (E:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3E (E:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
k

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3hp3F (F:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3F (F:)
vslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyl
ekaln

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3hp3G (G:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3G (G:)
vslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyl
ekaln

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3hp3H (H:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3H (H:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
kaln

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3hp3I (I:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3I (I:)
vslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyl
ekaln

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3hp3J (J:)
mkpvslsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiq
eylekaln

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp3J (J:)
slsyrcpcrffeshvaranvkhlkilntpncalqivarlknnnrqvcidpklkwiqeyle
kal