PDB entry 3hp1

View 3hp1 on RCSB PDB site
Description: Crystal structure of human dCK R104M/D133A in complex with L-dT and ADP
Class: transferase
Keywords: dCK, L-dT, DM-dCK, dCK Structure Function Studies, Nucleoside Kinase, Protein-NA complex, dCK drug designing, ATP-binding, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Transferase
Deposited on 2009-06-03, released 2009-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-06-16, with a file datestamp of 2009-06-12.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.21
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Deoxycytidine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27707 (Start-279)
      • engineered (123)
      • engineered (152)
    Domains in SCOPe 2.08: d3hp1a_
  • Heterogens: ADP, LLT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hp1A (A:)
mgsshhhhhhssglvprgshmatppkrsspsfsassegtrikkisiegniaagkstfvni
lkqlcedwevvpepvarwcnvqstqdefeeltmsqknggnvlqmmyekperwsftfqtya
clsmiraqlaslngklkdaekpvlffersvysaryifasnlyesecmnetewtiyqdwhd
wmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykheswllhrt
lktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

    Sequence, based on observed residues (ATOM records): (download) 
    >3hp1A (A:)
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqggnvlqmmyekperwsf
tfqtyaclsmiraqlaslngklkdaekpvlffersvysaryifasnlyesecmnetewti
yqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykhes
wllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl