PDB entry 3hoz

View 3hoz on RCSB PDB site
Description: Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine
Deposited on 2009-06-03, released 2009-07-28
The last revision was dated 2010-01-19, with a file datestamp of 2010-01-15.
Experiment type: XRAY
Resolution: 3.65 Å
R-factor: 0.21
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed RNA polymerase II subunit RPB1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA-directed RNA polymerase II subunit RPB2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA-directed RNA polymerase II subunit RPB3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA-directed RNA polymerase II subunit RPB4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: DNA-directed RNA polymerase II subunit RPB7
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA-directed RNA polymerase II subunit RPB9
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC5
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: DNA-directed RNA polymerase II subunit RPB11
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: DNA-directed RNA polymerases I, II, and III subunit RPABC4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: 5'-d(*ap*cp*tp*ap*cp*tp*tp*gp*ap*gp*cp*t)-3'
  • Chain 'P':
    Compound: 5'-r(*up*gp*cp*ap*up*up*u*cp*ap*ap*cp*cp*ap*gp*gp*cp*up*g)-3'
  • Chain 'T':
    Compound: 5'-d(*ap*gp*cp*tp*c*ap*ap*gp*tp*ap*gp*tp*tp*cp*tp*gp*cp*cp*(bru)p*gp*gp*tp*cp*ap*tp*t)-3'
  • Heterogens: ZN, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hozA (A:)
mvgqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgs
idrnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehne
lmrqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglk
lvgswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclp
vppppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhv
atymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnle
ldqvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskr
agdiqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspyna
dfdgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtf
ieldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllsp
kdngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhn
gfstgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvr
flneardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfv
drtlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrr
lvkaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvd
llntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvni
rriiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfcc
llrsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmt
lntfhfagvaskkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaieh
ttlksvtiaseiyydpdprstvipedeeiiqlhfslldeeaeqsfdqqspwllrleldra
amndkdltmgqvgerikqtfkndlfviwsedndekliircrvvrpksldaeteaeedhml
kkientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvp
gidptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqgg
ltsvtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtga
fdvmideeslvkympeqkiteiedgqdggvtpysnesglvnadldvkdelmfsplvdsgs
ndamaggftayggadygeatspfgaygeaptspgfgvsspgfsptsptysptspayspts
psysptspsysptspsysptspsysptspsysptspsysptspsysptspsysptspsys
ptspsysptspsysptspsysptspsysptspsysptspaysptspsysptspsysptsp
sysptspsysptspnysptspsysptspgyspgspayspkqdeqkhnenensr

    Sequence, based on observed residues (ATOM records):
    >3hozA (A:)
vgqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsi
drnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnel
mrqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglkl
vgswkkdepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvppppvrp
sisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvatymdndi
agqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleldqvgvpk
siaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskragdiqlqy
gwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadfdgdemn
lhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfieldqvln
mlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkdngmlii
dgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngfstgigd
tiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrflneardk
agrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdrtlphfs
kddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlvkaledi
mvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdllntdhtl
dpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirriiqnaq
qtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccllrsrlat
rrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtlkvtsgvp
rlkeilnvaknmktpsltvylepghaadqeqaklirsaiehttlksvtiaseiyydpdpr
stvipedeeiiqlhfsdqqspwllrleldraamndkdltmgqvgerikqtfkndlfviws
edndekliircrvvrpaeedhmlkkientmlenitlrgveniervvmmkydrkvpsptge
yvkepewvletdgvnlsevmtvpgidptriytnsfidimevlgieagraalykevynvia
sdgsyvnyrhmallvdvmttqggltsvtrhgfnrsntgalmrcsfeetveilfeagasae
lddcrgvsenvilgqmapigtgafdvmideeslvkymp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hozB (B:)
msdlansekyydedpygfedesapitaedswavisaffrekglvsqqldsfnqfvdytlq
diicedstlileqlaqhttesdnisrkyeisfgkiyvtkpmvnesdgvthalypqearlr
nltyssglfvdvkkrtyeaidvpgrelkyeliaeeseddsesgkvfigrlpimlrskncy
lseatesdlyklkecpfdmggyfiingsekvliaqersagnivqvfkkaapspishvaei
rsalekgsrfistlqvklygregssartikatlpyikqdipiviifralgiipdgeileh
icydvndwqmlemlkpcvedgfviqdretaldfigrrgtalgikkekriqyakdilqkef
lphitqlegfesrkafflgyminrlllcaldrkdqddrdhfgkkrldlagpllaqlfktl
fkkltkdifrymqrtveeahdfnmklainaktitsglkyalatgnwgeqkkamssragvs
qvlnrytysstlshlrrtntpigrdgklakprqlhnthwglvcpaetpegqacglvknls
lmscisvgtdpmpiitflsewgmepledyvphqspdatrvfvngvwhgvhrnparlmetl
rtlrrkgdinpevsmirdirekelkiftdagrvyrplfiveddeslghkelkvrkghiak
lmateyqdieggfedveeytwssllneglveyidaeeeesiliamqpedlepaeaneend
ldvdpakrirvshhattfthceihpsmilgvaasiipfpdhnqsprntyqsamgkqamgv
fltnynvrmdtmanilyypqkplgttrameylkfrelpagqnaivaiacysgynqedsmi
mnqssidrglfrslffrsymdqekkygmsitetfekpqrtntlrmkhgtydkldddglia
pgvrvsgedviigkttpispdeeelgqrtayhskrdastplrstengivdqvlvttnqdg
lkfvkvrvrttkipqigdkfasrhgqkgtigityrredmpftaegivpdliinphaipsr
mtvahliecllskvaalsgnegdaspftditvegiskllrehgyqsrgfevmynghtgkk
lmaqiffgptyyqrlrhmvddkiharargpmqvltrqpvegrsrdgglrfgemerdcmia
hgaasflkerlmeasdafrvhicgicglmtviaklnhnqfeckgcdnkidiyqihipyaa
kllfqelmamnitprlytdrsrdf

    Sequence, based on observed residues (ATOM records):
    >3hozB (B:)
desapitaedswavisaffrekglvsqqldsfnqfvdytlqdiicedstlieisfgkiyv
tkpmvnesdgvthalypqearlrnltyssglfvdvkkkvfigrlpimlrskncylseate
sdlyklkecpfdmggyfiingsekvliaqersagnivqvfkkaapspishvaeirsalek
gsrfistlqvklygregssartikatlpyikqdipiviifralgiipdgeilehicydvn
dwqmlemlkpcvedgfviqdretaldfigrkekriqyakdilqkeflphitqlegfesrk
afflgyminrlllcaldrkdqddrdhfgkkrldlagpllaqlfktlfkkltkdifrymqr
tvelainaktitsglkyalatgnwgeqkmssragvsqvlnrytysstlshlrrtntpigr
lakprqlhnthwglvcpaetpegqacglvknlslmscisvgtdpmpiitflsewgmeple
dyvphqspdatrvfvngvwhgvhrnparlmetlrtlrrkgdinpevsmirdirekelkif
tdagrvyrplfiveddeslghkelkvrkghiaklmateyqdeytwssllneglveyidae
eeesiliamqpedlepaeadvdpakrirvshhattfthceihpsmilgvaasiipfpdhn
qsprntyqsamgkqamgvfltnynvrmdtmanilyypqkplgttrameylkfrelpagqn
aivaiacysgynqedsmimnqssidrglfrslffrsymdqekkygmsitetfekpqrtnt
lrmkhgtydkldddgliapgvrvsgedviigkttpisskrdastplrstengivdqvlvt
tnqdglkfvkvrvrttkipqigdkfasrhgqkgtigityrredmpftaegivpdliinph
aipsrmtvahliecllskvaalsgnegdaspftditvegiskllrehgyqsrgfevmyng
htgkklmaqiffgptyyqrlrhmvddkiharargpmqvltrqpvegrsrdgglrfgemer
dcmiahgaasflkerlmeasdafrvhicgicglmtviaklnhnqfeckgcdnkidiyqih
ipyaakllfqelmamnitprlytdrsrdf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3hozC (C:)
mgshhhhhhsnsglndifeaqkiewhedtgseegpqvkireaskdnvdfilsnvdlaman
slrrvmiaeiptlaidsvevetnttvladefiahrlgliplqsmdieqleysrdcfcedh
cdkcsvvltlqafgesesttnvyskdlvivsnlmgrnighpiiqdkegngvlicklrkgq
elkltcvakkgiakehakwgpaaaiefeydpwnklkhtdywyeqdsakewpqsknceyed
ppnegdpfdykaqadtfymnvesvgsipvdqvvvrgidtlqkkvasillaltqmdqdkvn
fasgdnntasnmlgsnedvmmtgaeqdpysnasqmgntgsggydnaw

    Sequence, based on observed residues (ATOM records):
    >3hozC (C:)
eegpqvkireaskdnvdfilsnvdlamanslrrvmiaeiptlaidsvevetnttvladef
iahrlgliplqsmdieqleysrdcfcedhcdkcsvvltlqafgesesttnvyskdlvivs
nlmgrnighpiiqdkegngvlicklrkgqelkltcvakkgiakehakwgpaaaiefeydp
wnklkhtdywyeqdsakewpqsknceyedppnegdpfdykaqadtfymnvesvgsipvdq
vvvrgidtlqkkvasillaltqmdqd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3hozD (D:)
mnvststfqtrrrrlkkveeeenaatlqlgqefqlkqinhqgeeeelialnlsearlvik
ealverrrafkrsqkkhkkkhlkhenandettavededddldeddvnaddddfmhsetre
kelesidvlleqttggnnkdlkntmqyltnfsrfrdqetvgaviqllkstglhpfevaql
gslacdtadeaktlipslnnkisddelerilkelsnletly

    Sequence, based on observed residues (ATOM records):
    >3hozD (D:)
vststfqtrrrrlkkveeeenaatlqlgqefqlkqinhqgeeeelialnlsearlvikea
lverrrafkrsqkketrekelesidvlleqttggnnkdlkntmqyltnfsrfrdqetvga
viqllkstglhpfevaqlgslacdtadeaktlipslnnkisddelerilkelsnletly

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3hozE (E:)
mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
adpvalylglkrgevvkiirksetsgryasyricm

    Sequence, based on observed residues (ATOM records):
    >3hozE (E:)
dqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfq
anpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsam
klvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqra
dpvalylglkrgevvkiirksetsgryasyricm

  • Chain 'F':
    Sequence, based on SEQRES records:
    >3hozF (F:)
msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
amkelaekkiplvirrylpdgsfedwsveelivdl

    Sequence, based on observed residues (ATOM records):
    >3hozF (F:)
lkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplriamkelaek
kiplvirrylpdgsfedwsveelivdl

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >3hozG (G:)
mffikdlslnitlhpsffgprmkqylktklleevegsctgkfgyilcvldydnidiqrgr
ilptdgsaefnvkyravvfkpfkgevvdgtvvscsqhgfevqvgpmkvfvtkhlmpqdlt
fnagsnppsyqssedvitiksrirvkiegcisqvssihaigsikedylgai

  • Chain 'H':
    Sequence, based on SEQRES records:
    >3hozH (H:)
msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
llmrlegnyrnlnnlkqenayllirr

    Sequence, based on observed residues (ATOM records):
    >3hozH (H:)
msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
sslnltrswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyr
nlnnlkqenayllirr

  • Chain 'I':
    Sequence, based on SEQRES records:
    >3hozI (I:)
mttfrfcrdcnnmlypredkennrllfecrtcsyveeagsplvyrhelitnigetagvvq
digsdptlprsdrecpkchsrenvffqsqqrrkdtsmvlffvclscshiftsdqknkrtq
fs

    Sequence, based on observed residues (ATOM records):
    >3hozI (I:)
ttfrfcrdcnnmlypredkennrllfecrtcsyveeagsplvyrhelitnigetagvvqd
igsdptlprsdrecpkchsrenvffqsqqrrkdtsmvlffvclscshiftsdqknkrtq

  • Chain 'J':
    Sequence, based on SEQRES records:
    >3hozJ (J:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekrd

    Sequence, based on observed residues (ATOM records):
    >3hozJ (J:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynp

  • Chain 'K':
    Sequence, based on SEQRES records:
    >3hozK (K:)
mnapdrfelfllgegesklkidpdtkapnavvitfekedhtlgnliraellndrkvlfaa
ykvehpffarfklriqttegydpkdalknacnsiinklgalktnfetewnlqtlaaddaf

    Sequence, based on observed residues (ATOM records):
    >3hozK (K:)
mnapdrfelfllgegesklkidpdtkapnavvitfekedhtlgnliraellndrkvlfaa
ykvehpffarfklriqttegydpkdalknacnsiinklgalktnfetewnlqtla

  • Chain 'L':
    Sequence, based on SEQRES records:
    >3hozL (L:)
msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
tkrlvqfear

    Sequence, based on observed residues (ATOM records):
    >3hozL (L:)
atlkyicaecssklslsrtdavrckdcghrillkartkrlvqfear

  • Chain 'N':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.