PDB entry 3hom
View 3hom on RCSB PDB site
Description: Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor
Class: hormone
Keywords: beta-trefoil, Acetylation, Alternative splicing, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE
Deposited on
2009-06-02, released
2009-10-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-10-20, with a file datestamp of
2009-10-16.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.198
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: acidic fibroblast growth factor
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3homa1, d3homa2 - Chain 'B':
Compound: acidic fibroblast growth factor
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3homb1, d3homb2 - Heterogens: FMT, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3homA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylcmdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3homA (A:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylcmdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3homB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylcmdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3homB (B:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylcmdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv