PDB entry 3ho8

View 3ho8 on RCSB PDB site
Description: crystal structure of s. aureus pyruvate carboxylase in complex with coenzyme a
Deposited on 2009-06-01, released 2009-06-30
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate carboxylase
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: pycA, Pyruvate Carboxylase, SAV1114
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: pyruvate carboxylase
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: pycA, Pyruvate Carboxylase, SAV1114
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: pyruvate carboxylase
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: pycA, Pyruvate Carboxylase, SAV1114
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: pyruvate carboxylase
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: pycA, Pyruvate Carboxylase, SAV1114
    Database cross-references and differences (RAF-indexed):
  • Heterogens: COA, MN, BTI

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ho8A (A:)
mkqikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpa
esylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkv
karttaikadlpvipgtdgpiksyelakefaeeagfplmikatsggggkgmrivreesel
edafhrakseaeksfgnsevyieryidnpkhievqvigdehgnivhlferdcsvqrrhqk
vvevapsvglsptlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqveht
itemvtgidivktqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdt
gtiiayrssggfgvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremr
irgvktnipflinvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvting
fpnvekrpkpdyelasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttf
rdahqsllatrvrtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerl
rkaipnvlfqmllrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvan
eavqeagkisegticytgdilnpersniytleyyvklakeleregfhilaikdmagllkp
kaayeligelksavdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsa
nslyyalngfprhlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqys
nlsqqakslglgerfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvi
tdgykldfpesvvsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvre
lleeeqqgpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveiei
dkgkrliikletisepdengnrtiyyamngqarriyikdenvhtnanvkpkadksnpshi
gaqmpgsvtevkvsvgetvkanqplliteamkmettiqapfdgvikqvtvnngdtiatgd
llieiekatd

    Sequence, based on observed residues (ATOM records):
    >3ho8A (A:)
qikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpaes
ylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkvka
rttaikadlpvipgtdryidnpkhievqvigdehgnivhlferdcsvqrrhqkvvevaps
vglsptlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqvehtitemvtg
idivktqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdtgtiiayr
ssggfgvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremrirgvktn
ipflinvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvtingfpnvekr
pkpdyelasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttfrdahqsl
latrvrtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerlrkaipnv
lfqmllrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvaneavqeag
kisegticytgdilnpersniytleyyvklakeleregfhilaikdmagllkpkaayeli
gelksavdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsanslyyal
ngfprhlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqysnlsqqak
slglgerfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvitdgykld
fpesvvsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvrelleeeqq
gpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveieidkgkrli
ikletisepdengnrtiyyamngqarriyikden

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ho8B (B:)
mkqikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpa
esylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkv
karttaikadlpvipgtdgpiksyelakefaeeagfplmikatsggggkgmrivreesel
edafhrakseaeksfgnsevyieryidnpkhievqvigdehgnivhlferdcsvqrrhqk
vvevapsvglsptlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqveht
itemvtgidivktqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdt
gtiiayrssggfgvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremr
irgvktnipflinvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvting
fpnvekrpkpdyelasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttf
rdahqsllatrvrtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerl
rkaipnvlfqmllrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvan
eavqeagkisegticytgdilnpersniytleyyvklakeleregfhilaikdmagllkp
kaayeligelksavdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsa
nslyyalngfprhlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqys
nlsqqakslglgerfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvi
tdgykldfpesvvsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvre
lleeeqqgpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveiei
dkgkrliikletisepdengnrtiyyamngqarriyikdenvhtnanvkpkadksnpshi
gaqmpgsvtevkvsvgetvkanqplliteamkmettiqapfdgvikqvtvnngdtiatgd
llieiekatd

    Sequence, based on observed residues (ATOM records):
    >3ho8B (B:)
qikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpaes
ylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkvka
rttaikadlpvipidnpkhievqvigdehgnivhlferdcsvqrrhqkvvevapsvglsp
tlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqvehtitemvtgidivk
tqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdtgtiiayrssggf
gvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremrirgvktnipfli
nvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvtingfpnvekrpkpdy
elasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttfrdahqsllatrv
rtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerlrkaipnvlfqml
lrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvaneavqeagkiseg
ticytgdilnpersniytleyyvklakeleregfhilaikdmagllkpkaayeligelks
avdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsanslyyalngfpr
hlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqysnlsqqakslglg
erfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvitdgykldfpesv
vsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvrelleeeqqgpvte
qdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveieidkgkrliiklet
isepdengnrtiyyamngqarriyikden

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3ho8C (C:)
mkqikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpa
esylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkv
karttaikadlpvipgtdgpiksyelakefaeeagfplmikatsggggkgmrivreesel
edafhrakseaeksfgnsevyieryidnpkhievqvigdehgnivhlferdcsvqrrhqk
vvevapsvglsptlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqveht
itemvtgidivktqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdt
gtiiayrssggfgvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremr
irgvktnipflinvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvting
fpnvekrpkpdyelasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttf
rdahqsllatrvrtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerl
rkaipnvlfqmllrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvan
eavqeagkisegticytgdilnpersniytleyyvklakeleregfhilaikdmagllkp
kaayeligelksavdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsa
nslyyalngfprhlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqys
nlsqqakslglgerfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvi
tdgykldfpesvvsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvre
lleeeqqgpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveiei
dkgkrliikletisepdengnrtiyyamngqarriyikdenvhtnanvkpkadksnpshi
gaqmpgsvtevkvsvgetvkanqplliteamkmettiqapfdgvikqvtvnngdtiatgd
llieiekatd

    Sequence, based on observed residues (ATOM records):
    >3ho8C (C:)
qikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpaes
ylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkvka
rttaikadlpvipgtderyidnpkhievqvigdehgnivhlferdcsvqrrhqkvvevap
svglsptlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqvehtitemvt
gidivktqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdtgtiiay
rssggfgvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremrirgvkt
nipflinvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvtingfpnvek
rpkpdyelasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttfrdahqs
llatrvrtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerlrkaipn
vlfqmllrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvaneavqea
gkisegticytgdilnpersniytleyyvklakeleregfhilaikdmagllkpkaayel
igelksavdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsanslyya
lngfprhlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqysnlsqqa
kslglgerfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvitdgykl
dfpesvvsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvrelleeeq
qgpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveieidkgkrl
iikletisepdengnrtiyyamngqarriyikden

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3ho8D (D:)
mkqikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpa
esylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkv
karttaikadlpvipgtdgpiksyelakefaeeagfplmikatsggggkgmrivreesel
edafhrakseaeksfgnsevyieryidnpkhievqvigdehgnivhlferdcsvqrrhqk
vvevapsvglsptlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqveht
itemvtgidivktqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdt
gtiiayrssggfgvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremr
irgvktnipflinvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvting
fpnvekrpkpdyelasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttf
rdahqsllatrvrtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerl
rkaipnvlfqmllrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvan
eavqeagkisegticytgdilnpersniytleyyvklakeleregfhilaikdmagllkp
kaayeligelksavdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsa
nslyyalngfprhlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempggqys
nlsqqakslglgerfdevkdmyrrvnflfgdivkvtpsskvvgdmalymvqndldeqsvi
tdgykldfpesvvsffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvre
lleeeqqgpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveiei
dkgkrliikletisepdengnrtiyyamngqarriyikdenvhtnanvkpkadksnpshi
gaqmpgsvtevkvsvgetvkanqplliteamkmettiqapfdgvikqvtvnngdtiatgd
llieiekatd

    Sequence, based on observed residues (ATOM records):
    >3ho8D (D:)
qikkllvanrgeiairifraaaeldistvaiysnedksslhrykadesylvgsdlgpaes
ylnieriidvakqanvdaihpgygflseneqfarrcaeegikfigphlehldmfgdkvka
rttaikadlpvipidnpkhievqvigdehgnivhlferdcsvqrrhqkvvevapsvglsp
tlrqricdaaiqlmenikyvnagtveflvsgdefffievnprvqvehtitemvtgidivk
tqilvaagadlfgeeinmpqqkdittlgyaiqcrittedplndfmpdtgtiiayrssggf
gvrldagdgfqgaeispyydsllvklsthaisfkqaeekmvrslremrirgvktnipfli
nvmknkkftsgdyttkfieetpelfdiqpsldrgtktleyignvtingfpnvekrpkpdy
elasiptvssskiasfsgtkqlldevgpkgvaewvkkqddvlltdttfrdahqsllatrv
rtkdminiasktadvfkdgfslemwggatfdvaynflkenpwerlerlrkaipnvlfqml
lrasnavgyknypdnvihkfvqesakagidvfrifdslnwvdqmkvaneavqeagkiseg
ticytgdilnpersniytleyyvklakeleregfhilaikdmagllkpkaayeligelks
avdlpihlhthdtsgnglltykqaidagvdiidtavasmsgltsqpsanslyyalngfpr
hlrtdiegmeslshywstvrtyysdfesdikspnteiyqhempgglglgerfdevkdmkv
tpsskvvffkgeigqpvngfnkdlqavilkgqealtarpgeylepvdfekvrelleeeqq
gpvteqdiisyvlypkvyeqyiqtrnqygnlslldtptfffgmrngetveieidkgkrli
ikletisepdengnrtiyyamngqarriyikden