PDB entry 3ho1

View 3ho1 on RCSB PDB site
Description: crystal structure of t. thermophilus argonaute n546 mutant protein complexed with dna guide strand and 12-nt rna target strand
Deposited on 2009-06-01, released 2009-10-06
The last revision was dated 2021-10-13, with a file datestamp of 2021-10-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.22
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Argonaute
    Species: Thermus thermophilus [TaxId:262724]
    Gene: TT_P0026
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q746M7 (0-684)
      • engineered mutation (545)
  • Chain 'X':
    Compound: 5'-d(p*tp*gp*ap*gp*gp*tp*ap*gp*tp*ap*gp*gp*tp*tp*gp*tp*ap*t*ap*gp*t)-3'
  • Chain 'Y':
    Compound: 5'-r(p*cp*cp*up*ap*cp*up*ap*cp*cp*up*cp*g)-3'
  • Heterogens: MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ho1A (A:)
mnhlgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrm
gdglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqer
lrrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemsle
awlaqghplpkrvrnaydrrtwellrlgeedpkelplpgglslldyhaskgrlqgreggr
vawvadpkdprkpiphltgllvpvltledlheeegslalslpweerrrrtreiaswigrr
lglgtpeavraqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpef
lrrallrafgasgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnr
lkalllreglpsqilnvplreeerhrwenallgllakaglqvvalsgaypaelavgfdag
gresfrfggaacavggdgghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsr
vlllrngrvpqdefalalealaregiaydlvsvrksgggrvypvqgrladglyvpledkt
fllltvhrdfrgtprplklvheagdtplealahqifhltrlypasgfafprlpaplhlad
rlvkevgrlgirhlkevdreklffv

    Sequence, based on observed residues (ATOM records):
    >3ho1A (A:)
nhlgktevflnrfalrplnpeelrpwrlevvldpppgreevypllaqvarraggvtvrmg
dglaswsppevlvlegtlarmgqtyayrlypkgrrpldpkdpgersvlsalarrllqerl
rrlegvwveglavyrrehargpgwrvlggavldlwvsdsgafllevdpayrilcemslea
wlaqghplpkrvrnaydrrtwellrlgeedpkelslldyhaskgrlqgreggrvawvadp
kkpiphltgllvpvltledlheeegslalslpweerrrrtreiaswigrrlglgtpeavr
aqayrlsipklmgrravskpadalrvgfyraqetalallrldgaqgwpeflrrallrafg
asgaslrlhtlhahpsqglafrealrkakeegvqavlvltppmawedrnrlkalllregl
psqilnvplreeerhrwenallgllakaglqvvalsgaypaelavgfdaggresfrfgga
acavggghllwtlpeaqageripqevvwdlleetlwafrrkagrlpsrvlllrngrvpqd
efalalealaregiaydlvsvrksgggrvypvqgrladglyvpledktfllltvhrdfrg
tprplklvheagdtplealahqifhltrlypasgfafprlpaplhladrlvkevgrlgir
hlkevdreklffv

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.