PDB entry 3hnd

View 3hnd on RCSB PDB site
Description: crystal structure of human ribonucleotide reductase 1 bound to the effector ttp and substrate gdp
Deposited on 2009-05-31, released 2011-02-23
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 3.21 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonucleoside-diphosphate reductase large subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RR1, RRM1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ribonucleoside-diphosphate reductase large subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RR1, RRM1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, TTP, GDP, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hndA (A:)
mhvikrdgrqervmfdkitsriqklcyglnmdfvdpaqitmkviqglysgvttveldtla
aetaatlttkhpdyailaariavsnlhketkkvfsdvmedlynyinphngkhspmvakst
ldivlankdrlnsaiiydrdfsynyfgfktlersyllkingkvaerpqhmlmrvsvgihk
edidaaietynllserwfthasptlfnagtnrpqlsscfllsmkddsiegiydtlkqcal
isksaggigvavsciratgsyiagtngnsnglvpmlrvynntaryvdqggnkrpgafaiy
lepwhldifefldlkkntgkeeqrardlffalwipdlfmkrvetnqdwslmcpnecpgld
evwgeefeklyasyekqgrvrkvvkaqqlwyaiiesqtetgtpymlykdscnrksnqqnl
gtikcsnlcteiveytskdevavcnlaslalnmyvtsehtydfkklaevtkvvvrnlnki
idinyypvpeaclsnkrhrpigigvqgladafilmrypfesaeaqllnkqifetiyygal
eascdlakeqgpyetyegspvskgilqydmwnvtptdlwdwkvlkekiakygirnsllia
pmptastaqilgnnesiepytsniytrrvlsgefqivnphllkdlterglwheemknqii
acngsiqsipeipddlkqlyktvweisqktvlkmaaergafidqsqslnihiaepnygkl
tsmhfygwkqglktgmyylrtrpaanpiqftlnkeklkdkekvskeeeekerntaamvcs
lenrdeclmcgs

    Sequence, based on observed residues (ATOM records):
    >3hndA (A:)
mfdkitsriqklcyglnmdfvdpaqitmkviqglysgvttveldtlaaetaatlttkhpd
yailaariavsnlhketkkvfsdvmedlynyinphngkhspmvakstldivlankdrlns
aiiydrdfsynyfgfktlersyllkingkvaerpqhmlmrvsvgihkedidaaietynll
serwfthasptlfnagtnrpqlsscfllsmkddsiegiydtlkqcalisksaggigvavs
ciratgsyiagtngnsnglvpmlrvynntaryvdqggnkrpgafaiylepwhldifefld
lkkntgkeeqrardlffalwipdlfmkrvetnqdwslmcpnecpgldevwgeefeklyas
yekqgrvrkvvkaqqlwyaiiesqtetgtpymlykdscnrksnqqnlgtikcsnlcteiv
eytskdevavcnlaslalnmyvtsehtydfkklaevtkvvvrnlnkiidinyypvpeacl
snkrhrpigigvqgladafilmrypfesaeaqllnkqifetiyygaleascdlakeqgpy
etyegspvskgilqydmwnvtptdlwdwkvlkekiakygirnslliapmptastaqilgn
nesiepytsniytrrvlsgefqivnphllkdlterglwheemknqiiacngsiqsipeip
ddlkqlyktvweisqktvlkmaaergafidqsqslnihiaepnygkltsmhfygwkqglk
tgmyylrtr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hndB (B:)
mhvikrdgrqervmfdkitsriqklcyglnmdfvdpaqitmkviqglysgvttveldtla
aetaatlttkhpdyailaariavsnlhketkkvfsdvmedlynyinphngkhspmvakst
ldivlankdrlnsaiiydrdfsynyfgfktlersyllkingkvaerpqhmlmrvsvgihk
edidaaietynllserwfthasptlfnagtnrpqlsscfllsmkddsiegiydtlkqcal
isksaggigvavsciratgsyiagtngnsnglvpmlrvynntaryvdqggnkrpgafaiy
lepwhldifefldlkkntgkeeqrardlffalwipdlfmkrvetnqdwslmcpnecpgld
evwgeefeklyasyekqgrvrkvvkaqqlwyaiiesqtetgtpymlykdscnrksnqqnl
gtikcsnlcteiveytskdevavcnlaslalnmyvtsehtydfkklaevtkvvvrnlnki
idinyypvpeaclsnkrhrpigigvqgladafilmrypfesaeaqllnkqifetiyygal
eascdlakeqgpyetyegspvskgilqydmwnvtptdlwdwkvlkekiakygirnsllia
pmptastaqilgnnesiepytsniytrrvlsgefqivnphllkdlterglwheemknqii
acngsiqsipeipddlkqlyktvweisqktvlkmaaergafidqsqslnihiaepnygkl
tsmhfygwkqglktgmyylrtrpaanpiqftlnkeklkdkekvskeeeekerntaamvcs
lenrdeclmcgs

    Sequence, based on observed residues (ATOM records):
    >3hndB (B:)
hvikrdgrqervmfdkitsriqklcyglnmdfvdpaqitmkviqglyvttveldtlaaet
aatlttkhpdyailaariavsnlhketkkvfsdvmedlynyinphngkhspmvakstldi
vlankdrlnsaiiydrdfsynyfgfktlersyllkingkvaerpqhmlmrvsvgihkedi
daaietynllserwfthasptlfnagtnrpqlsscfllsmkddsiegiydtlkqcalisk
saggigvavsciratgsyiagtngnsnglvpmlrvynntaryvdqggnkrpgafaiylep
whldifefldlkkntgkeeqrardlffalwipdlfmkrvetnqdwslmcpnecpgldevw
geefeklyasyekqgrvrkvvkaqqlwyaiiesqtetgtpymlykdscnrksnqqnlgti
kcsnlcteiveytskdevavcnlaslalnmyvtsehtydfkklaevtkvvvrnlnkiidi
nyypvpeaclsnkrhrpigigvqgladafilmrypfesaeaqllnkqifetiyygaleas
cdlakeqgpyetyegspvskgilqydmwnvtptdlwdwkvlkekiakygirnslliapmp
tastaqilgnnesiepytsniytrrefqivnphllkdlterglwheemknqiiacngsiq
sipeipddlkqlyktvweisqktvlkmaaergafidqsqslnihiaepnygkltsmhfyg
wkqglktgmyylrtr