PDB entry 3hli

View 3hli on RCSB PDB site
Description: diisopropyl fluorophosphatase (DFPase), active site mutants
Class: hydrolase
Keywords: phosphotriesterase, beta propeller, calcium binding, Calcium, Hydrolase, Metal-binding
Deposited on 2009-05-27, released 2009-11-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-12-08, with a file datestamp of 2009-12-04.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.205
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.08: d3hlia_
  • Chain 'B':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.08: d3hlib_
  • Chain 'C':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.08: d3hlic_
  • Chain 'D':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.08: d3hlid_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hliA (A:)
meipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hliA (A:)
eipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktvi
ckpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcnd
cafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrh
mndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllv
anwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrng
kkqycetlkfgif

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hliB (B:)
meipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hliB (B:)
ipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hliC (C:)
meipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hliC (C:)
ipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hliD (D:)
meipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hliD (D:)
ipvieplftkvtedipgaegpvfdkngdfyivapdvevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif