PDB entry 3hlh

View 3hlh on RCSB PDB site
Description: Diisopropyl fluorophosphatase (DFPase), active site mutants
Class: hydrolase
Keywords: phosphotriesterase, beta propeller, calcium binding, Calcium, Hydrolase, Metal-binding
Deposited on 2009-05-27, released 2009-11-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-12-08, with a file datestamp of 2009-12-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.195
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.07: d3hlha_
  • Chain 'B':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.07: d3hlhb_
  • Chain 'C':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.07: d3hlhc_
  • Chain 'D':
    Compound: Diisopropyl-fluorophosphatase
    Species: Loligo vulgaris [TaxId:6622]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIG4 (Start-313)
      • engineered (36)
      • engineered (143)
      • engineered (145)
      • engineered (194)
    Domains in SCOPe 2.07: d3hlhd_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hlhA (A:)
meipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hlhA (A:)
ipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hlhB (B:)
meipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hlhB (B:)
ipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hlhC (C:)
meipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hlhC (C:)
ipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hlhD (D:)
meipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktv
ickpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcn
dcafdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavr
hmndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnll
vanwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrn
gkkqycetlkfgif

    Sequence, based on observed residues (ATOM records): (download) 
    >3hlhD (D:)
ipvieplftkvtedipgaegpvfdkngdfyivapavevngkpageilridlktgkktvic
kpevngyggipagcqcdrdanqlfvadmrlgllvvqtdgtfeeiakkdsegrrmqgcndc
afdyegnlwitapagevapadatasmqekfgsiycfttdgqmiqvdtafqfpngiavrhm
ndgrpyqlivaemptkklwsydikgpakienkkvwghipgtheggadgmdfdednnllva
nwgsshievfgpdggqpkmrircpfekpsnlhfkpqtktifvtehennavwkfewqrngk
kqycetlkfgif