PDB entry 3hl5
View 3hl5 on RCSB PDB site
Description: Crystal structure of XIAP BIR3 with CS3
Class: ligase
Keywords: BIR, IAP, apoptosis, small molecule drug discovery, structure-based drug design, Ligase, Metal-binding, Phosphoprotein, Protease inhibitor, Thiol protease inhibitor, Ubl conjugation pathway, Zinc-finger
Deposited on
2009-05-26, released
2009-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.179
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: baculoviral iap repeat-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: API3, BIRC4, IAP3, XIAP
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3hl5a1, d3hl5a2 - Chain 'B':
Compound: baculoviral iap repeat-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: API3, BIRC4, IAP3, XIAP
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3hl5b_ - Heterogens: ZN, 9JZ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3hl5A (A:)
gshmlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwk
psedpweqhakwypgckylleqkgqeyinnihlth
Sequence, based on observed residues (ATOM records): (download)
>3hl5A (A:)
shmlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkp
sedpweqhakwypgckylleqkgqeyinnihlth
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3hl5B (B:)
gshmlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwk
psedpweqhakwypgckylleqkgqeyinnihlth
Sequence, based on observed residues (ATOM records): (download)
>3hl5B (B:)
lprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsed
pweqhakwypgckylleqkgqeyinnihlt