PDB entry 3hl2

View 3hl2 on RCSB PDB site
Description: The crystal structure of the human SepSecS-tRNASec complex
Class: transferase
Keywords: selenocysteine, tRNASec, SepSecS, protein-RNA complex, Alternative splicing, Cytoplasm, Protein biosynthesis, Pyridoxal phosphate, Selenium, Transferase
Deposited on 2009-05-26, released 2009-10-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: O-phosphoseryl-tRNA(Sec) selenium transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SEPSECS, TRNP48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hl2a_
  • Chain 'B':
    Compound: O-phosphoseryl-tRNA(Sec) selenium transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SEPSECS, TRNP48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hl2b_
  • Chain 'C':
    Compound: O-phosphoseryl-tRNA(Sec) selenium transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SEPSECS, TRNP48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hl2c_
  • Chain 'D':
    Compound: O-phosphoseryl-tRNA(Sec) selenium transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SEPSECS, TRNP48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hl2d_
  • Chain 'E':
    Compound: tRNASec
    Species: Homo sapiens [TaxId:9606]
  • Heterogens: PLR, TS6, SEP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hl2A (A:)
mnresfaagerlvspayvrqgcearrshehlirlllekgkcpengwdestlelflhelai
mdsnnflgncgvgeregrvasalvarrhyrfihgigrsgdisavqpkaagssllnkitns
lvldiiklagvhtvancfvvpmatgmsltlcfltlrhkrpkakyiiwpridqkscfksmi
tagfepvvienvlegdelrtdlkaveakvqelgpdcilcihsttscfaprvpdrleelav
icanydiphivnnaygvqsskcmhliqqgarvgridafvqsldknfmvpvggaiiagfnd
sfiqeiskmypgrasaspsldvlitllslgsngykkllkerkemfsylsnqikklseayn
erllhtphnpislamtlktldehrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfr
gfmshtnnypcaylnaasaigmkmqdvdlfikrldrclkavrkerskesddnydktedvd
ieemalkldnvlldtyqdass

    Sequence, based on observed residues (ATOM records): (download) 
    >3hl2A (A:)
earrshehlirlllekgkcpengwdestlelflhelaimdsnnflgncgvgeregrvasa
lvarrhyrfihgigrsgdisavqpkaagssllnkitnslvldiiklagvhtvancfvvpm
atgmsltlcfltlrhkrpkakyiiwpridqkscfksmitagfepvvienvlegdelrtdl
kaveakvqelgpdcilcihsttscfaprvpdrleelavicanydiphivnnaygvqsskc
mhliqqgarvgridafvqsldknfmvpvggaiiagfndsfiqeiskmypgrasaspsldv
litllslgsngykkllkerkemfsylsnqikklseaynerllhtphnpislamtlktlde
hrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfrgfmshtnnypcaylnaasaigm
kmqdvdlfikrldrclkavrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hl2B (B:)
mnresfaagerlvspayvrqgcearrshehlirlllekgkcpengwdestlelflhelai
mdsnnflgncgvgeregrvasalvarrhyrfihgigrsgdisavqpkaagssllnkitns
lvldiiklagvhtvancfvvpmatgmsltlcfltlrhkrpkakyiiwpridqkscfksmi
tagfepvvienvlegdelrtdlkaveakvqelgpdcilcihsttscfaprvpdrleelav
icanydiphivnnaygvqsskcmhliqqgarvgridafvqsldknfmvpvggaiiagfnd
sfiqeiskmypgrasaspsldvlitllslgsngykkllkerkemfsylsnqikklseayn
erllhtphnpislamtlktldehrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfr
gfmshtnnypcaylnaasaigmkmqdvdlfikrldrclkavrkerskesddnydktedvd
ieemalkldnvlldtyqdass

    Sequence, based on observed residues (ATOM records): (download) 
    >3hl2B (B:)
gcearrshehlirlllekgkcpengwdestlelflhelaimdsnnflgncgvgeregrva
salvarrhyrfihgigrsgdisavqpkaagssllnkitnslvldiiklagvhtvancfvv
pmatgmsltlcfltlrhkrpkakyiiwpridqkscfksmitagfepvvienvlegdelrt
dlkaveakvqelgpdcilcihsttscfaprvpdrleelavicanydiphivnnaygvqss
kcmhliqqgarvgridafvqsldknfmvpvggaiiagfndsfiqeiskmypgrasaspsl
dvlitllslgsngykkllkerkemfsylsnqikklseaynerllhtphnpislamtlktl
dehrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfrgfmshtnnypcaylnaasai
gmkmqdvdlfikrldrclkavrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3hl2C (C:)
mnresfaagerlvspayvrqgcearrshehlirlllekgkcpengwdestlelflhelai
mdsnnflgncgvgeregrvasalvarrhyrfihgigrsgdisavqpkaagssllnkitns
lvldiiklagvhtvancfvvpmatgmsltlcfltlrhkrpkakyiiwpridqkscfksmi
tagfepvvienvlegdelrtdlkaveakvqelgpdcilcihsttscfaprvpdrleelav
icanydiphivnnaygvqsskcmhliqqgarvgridafvqsldknfmvpvggaiiagfnd
sfiqeiskmypgrasaspsldvlitllslgsngykkllkerkemfsylsnqikklseayn
erllhtphnpislamtlktldehrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfr
gfmshtnnypcaylnaasaigmkmqdvdlfikrldrclkavrkerskesddnydktedvd
ieemalkldnvlldtyqdass

    Sequence, based on observed residues (ATOM records): (download) 
    >3hl2C (C:)
qgcearrshehlirlllekgkcpengwdestlelflhelaimdsnnflgncgvgeregrv
asalvarrhyrfihgigrsgdisavqpkaagssllnkitnslvldiiklagvhtvancfv
vpmatgmsltlcfltlrhkrpkakyiiwpridqkscfksmitagfepvvienvlegdelr
tdlkaveakvqelgpdcilcihsttscfaprvpdrleelavicanydiphivnnaygvqs
skcmhliqqgarvgridafvqsldknfmvpvggaiiagfndsfiqeiskmypgrasasps
ldvlitllslgsngykkllkerkemfsylsnqikklseaynerllhtphnpislamtlkt
ldehrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfrgfmshtnnypcaylnaasa
igmkmqdvdlfikrldrclkavrke

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3hl2D (D:)
mnresfaagerlvspayvrqgcearrshehlirlllekgkcpengwdestlelflhelai
mdsnnflgncgvgeregrvasalvarrhyrfihgigrsgdisavqpkaagssllnkitns
lvldiiklagvhtvancfvvpmatgmsltlcfltlrhkrpkakyiiwpridqkscfksmi
tagfepvvienvlegdelrtdlkaveakvqelgpdcilcihsttscfaprvpdrleelav
icanydiphivnnaygvqsskcmhliqqgarvgridafvqsldknfmvpvggaiiagfnd
sfiqeiskmypgrasaspsldvlitllslgsngykkllkerkemfsylsnqikklseayn
erllhtphnpislamtlktldehrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfr
gfmshtnnypcaylnaasaigmkmqdvdlfikrldrclkavrkerskesddnydktedvd
ieemalkldnvlldtyqdass

    Sequence, based on observed residues (ATOM records): (download) 
    >3hl2D (D:)
earrshehlirlllekgkcpengwdestlelflhelaimdsnnflgncgvgeregrvasa
lvarrhyrfihgigrsgdisavqpkaagssllnkitnslvldiiklagvhtvancfvvpm
atgmsltlcfltlrhkrpkakyiiwpridqkscfksmitagfepvvienvlegdelrtdl
kaveakvqelgpdcilcihsttscfaprvpdrleelavicanydiphivnnaygvqsskc
mhliqqgarvgridafvqsldknfmvpvggaiiagfndsfiqeiskmypgrasaspsldv
litllslgsngykkllkerkemfsylsnqikklseaynerllhtphnpislamtlktlde
hrdkavtqlgsmlftrqvsgarvvplgsmqtvsgytfrgfmshtnnypcaylnaasaigm
kmqdvdlfikrldrclkavrk

  • Chain 'E':
    No sequence available.