PDB entry 3hkv

View 3hkv on RCSB PDB site
Description: human poly(adp-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide
Deposited on 2009-05-26, released 2009-06-16
The last revision was dated 2021-11-10, with a file datestamp of 2021-11-05.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly [ADP-ribose] polymerase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53GL7 (1-209)
      • expression tag (0)
      • engineered mutation (114)
      • engineered mutation (171)
      • expression tag (210-216)
  • Chain 'B':
    Compound: Poly [ADP-ribose] polymerase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP10
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53GL7 (1-209)
      • expression tag (0)
      • engineered mutation (114)
      • engineered mutation (171)
      • expression tag (210-216)
  • Heterogens: PO4, NA, 3AB, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3hkvA (A:)
magqtlkgpwnnlerlaentgefqevvrafydtldaarssirvvrvervshpllqqqyel
yrerllqrcerrpveqvlyhgttapavpdicahgfnrsfcgrnatvygkgvyfakrasls
vqdrysppnadghkavfvarvltgdygqgrrglrapplrgpghvllrydsamdcicqpsi
fvifhdtqalpthlitcehvpraspddpsgahhhhhh

    Sequence, based on observed residues (ATOM records):
    >3hkvA (A:)
wnnlerlaentgefqevvrafydtldaarssirvvrvervshpllqqqyelyrerllqrc
errpveqvlyhgttapavpdicahgfnrsfcgrnatvygkgvyfakraslsvqdrysppn
adghkavfvarvltgdygqgrrglrapplrgpghvllrydsamdcicqpsifvifhdtqa
lpthlitcehvp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3hkvB (B:)
magqtlkgpwnnlerlaentgefqevvrafydtldaarssirvvrvervshpllqqqyel
yrerllqrcerrpveqvlyhgttapavpdicahgfnrsfcgrnatvygkgvyfakrasls
vqdrysppnadghkavfvarvltgdygqgrrglrapplrgpghvllrydsamdcicqpsi
fvifhdtqalpthlitcehvpraspddpsgahhhhhh

    Sequence, based on observed residues (ATOM records):
    >3hkvB (B:)
nnlerlaentgefqevvrafydtldaarssirvvrvervshpllqqqyelyrerllqrce
rrpveqvlyhgttapavpdicahgfnrsfcgrnatvygkgvyfakraslsvqdrysppna
dghkavfvarvltgdygqgrrglrapplrgpghvllrydsamdcicqpsifvifhdtqal
pthlitcehvp