PDB entry 3hj0
View 3hj0 on RCSB PDB site
Description: Transthyretin in complex with a covalent small molecule kinetic stabilizer
Class: hormone
Keywords: Hormone, Growth Factor, Amyloid, Disease mutation, Gamma-carboxyglutamic acid, Glycoprotein, Polyneuropathy, Retinol-binding, Secreted, Thyroid hormone, Transport, Vitamin A
Deposited on
2009-05-20, released
2009-12-22
The last revision prior to the SCOPe 2.06 freeze date was dated
2014-11-19, with a file datestamp of
2014-11-14.
Experiment type: XRAY
Resolution: 1.34 Å
R-factor: 0.149
AEROSPACI score: 0.67
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: PALB, Transthyretin, TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3hj0a_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: PALB, Transthyretin, TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3hj0b_ - Heterogens: A93, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3hj0A (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3hj0A (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3hj0B (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3hj0B (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn