PDB entry 3hih

View 3hih on RCSB PDB site
Description: Structure of human Plk1-PBD with glycerol and sulfate in the phophopeptide binding site
Class: transferase
Keywords: kinase, phosphopeptide-binding domain, transferase, serine threonine protein kinase, ATP-binding, Cell cycle, Cell division, Mitosis, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase
Deposited on 2009-05-20, released 2009-06-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.188
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK, PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hiha1, d3hiha2
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK, PLK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hihb1, d3hihb2
  • Heterogens: SO4, GOL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3hihA (A:)
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svgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehl
lkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaav
tyidekrdfrtyrlslleeygcckelasrlryartmvdkllss

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hihB (B:)
dchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdn
svgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehl
lkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaav
tyidekrdfrtyrlslleeygcckelasrlryartmvdkllss

    Sequence, based on observed residues (ATOM records): (download) 
    >3hihB (B:)
dchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdn
svgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehl
lkaganirarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidekr
dfrtyrlslleeygcckelasrlryartmvdkllss