PDB entry 3hhr

View 3hhr on RCSB PDB site
Description: human growth hormone and extracellular domain of its receptor: crystal structure of the complex
Class: hormone/receptor
Keywords: hormone/receptor
Deposited on 1993-12-30, released 1994-04-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.221
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: human growth hormone
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hhra_
  • Chain 'B':
    Compound: HUMAN GROWTH HORMONE RECEPTOR (hGHbp)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hhrb1, d3hhrb2
  • Chain 'C':
    Compound: HUMAN GROWTH HORMONE RECEPTOR (hGHbp)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3hhrc1, d3hhrc2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3hhrA (A:)
    fptiplsrlfdnamlrahrlhqlafdtyqefeeayipkeqkysflqnpqtslcfsesipt
    psnreetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
    iqtlmgrledgsprtgqifkqtyskfdtnshnddallknygllycfrkdmdkvetflriv
    qcrsvegscg
    

    Sequence, based on observed residues (ATOM records): (download)
    >3hhrA (A:)
    fptiplsrlfdnamlrahrlhqlafdtyqefeeayipkeqkysflqnpqtslcfsesipt
    psnreetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
    iqtlmgrledgsprtgqifkqtyskfdtdallknygllycfrkdmdkvetflrivqcrsv
    egscg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3hhrB (B:)
    epkftkcrsperetfschwtdevhhgtknlgpiqlfytrrntqewtqewkecpdyvsage
    nscyfnssftsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgiha
    diqvrweaprnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevr
    vrskqrnsgnygefsevlyvtlpqm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3hhrB (B:)
    epkftkcrsperetfschwtdevhhgpiqlfytrrntewtqewkecpdyvsagenscyfn
    ssftsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrw
    eaprnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqr
    nsgnygefsevlyvtlp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3hhrC (C:)
    epkftkcrsperetfschwtdevhhgtknlgpiqlfytrrntqewtqewkecpdyvsage
    nscyfnssftsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgiha
    diqvrweaprnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevr
    vrskqrnsgnygefsevlyvtlpqm
    

    Sequence, based on observed residues (ATOM records): (download)
    >3hhrC (C:)
    epkftkcrsperetfschwtdevhhgpiqlfytrrntqewkecpdyvsagenscyfnssf
    tsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrweap
    rnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsg
    nygefsevlyvtlpqm