PDB entry 3hfb

View 3hfb on RCSB PDB site
Description: Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193
Class: oxidoreductase
Keywords: Tryptophan Hydroxylase type 1, Iron, Metal-binding, Monooxygenase, Oxidoreductase, Phosphoprotein, Serotonin biosynthesis
Deposited on 2009-05-11, released 2010-04-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-03-28, with a file datestamp of 2012-03-23.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: 0.218
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan 5-hydroxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17752 (0-289)
      • engineered (0)
      • engineered (75)
    Domains in SCOPe 2.08: d3hfba_
  • Heterogens: FE, ML4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hfbA (A:)
svpwfpkkisdldhcanrvlmygseldadhpgfkdnvyrkrrkyfadlamnykhgdpipk
vefteeeiktwgtvfrelnklypthacreylknlpllskycgyrednipqledvsnflke
rtgfsirpvagylsprdflsglafrvfhctqyvrhssdpfytpepdtchellghvpllae
psfaqfsqeiglaslgaseeavqklatcyfftvefglckqdgqlrvfgagllssiselkh
alsghakvkpfdpkitckqeclittfqdvyfvsesfedakekmreftkti

    Sequence, based on observed residues (ATOM records): (download) 
    >3hfbA (A:)
svpwfpkkisdldhcanrdnvyrkrrkyfadlamnykhgdpipkvefteeeiktwgtvfr
elnklypthacreylknlpllskycgyrednipqledvsnflkertgfsirpvagylspr
dflsglafrvfhctqyvrhssdpfytpepdtchellghvpllaepsfaqfsqeiglaslg
aseeavqklatcyfftvefglckqdgqlrvfgagllssiselkhalsghakvkpfdpkit
ckqeclittfqdvyfvsesfedakekmreftkti