PDB entry 3hf8

View 3hf8 on RCSB PDB site
Description: Crystal structure of human tryoptophan hydroxylase type 1 with bound LP-533401 and Fe
Class: oxidoreductase
Keywords: TRYOPTOPHAN HYDROXYLASE TYPE 1, Iron, Metal-binding, Monooxygenase, Oxidoreductase, Phosphoprotein, Serotonin biosynthesis
Deposited on 2009-05-11, released 2010-04-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-03-28, with a file datestamp of 2012-03-23.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.199
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan 5-hydroxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17752 (0-289)
      • conflict (0)
      • conflict (75)
    Domains in SCOPe 2.08: d3hf8a_
  • Heterogens: FE, ML0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hf8A (A:)
svpwfpkkisdldhcanrvlmygseldadhpgfkdnvyrkrrkyfadlamnykhgdpipk
vefteeeiktwgtvfrelnklypthacreylknlpllskycgyrednipqledvsnflke
rtgfsirpvagylsprdflsglafrvfhctqyvrhssdpfytpepdtchellghvpllae
psfaqfsqeiglaslgaseeavqklatcyfftvefglckqdgqlrvfgagllssiselkh
alsghakvkpfdpkitckqeclittfqdvyfvsesfedakekmreftkti

    Sequence, based on observed residues (ATOM records): (download) 
    >3hf8A (A:)
svpwfpkkisdldhcanrdnvyrkrrkyfadlamnykhgdpipkvefteeeiktwgtvfr
elnklypthacreylknlpllskycgyrednipqledvsnflkertgfsirpvagylspr
dflsglafrvfhctqyvrhssdpfytpepdtchellghvpllaepsfaqfsqeiglaslg
aseeavqklatcyfftvefglckqdgqlrvfgagllssiselkhalsghakvkpfdpkit
ckqeclittfqdvyfvsesfedakekmreftkti