PDB entry 3her

View 3her on RCSB PDB site
Description: Human prion protein variant F198S with V129
Class: membrane protein
Keywords: Prion Protein, Cell membrane, Disease mutation, Disulfide bond, Glycoprotein, Golgi apparatus, GPI-anchor, Lipoprotein, Membrane, Polymorphism, Prion, MEMBRANE PROTEIN
Deposited on 2009-05-10, released 2010-01-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: major prion protein
    Species: Homo sapiens [TaxId:9606]
    Gene: PRNP, PRIP, PRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04156
      • variant (39)
      • engineered (108)
    Domains in SCOPe 2.08: d3hera_
  • Chain 'B':
    Compound: major prion protein
    Species: Homo sapiens [TaxId:9606]
    Gene: PRNP, PRIP, PRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04156
      • variant (39)
      • engineered (108)
    Domains in SCOPe 2.08: d3herb_
  • Heterogens: CD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3herA (A:)
gqgggthsqwnkpskpktnmkhmagaaaagavvgglggyvlgsamsrpiihfgsdyedry
yrenmhrypnqvyyrpmdeysnqnnfvhdcvnitikqhtvttttkgenstetdvkmmerv
veqmcitqyeresqayyqrgss

    Sequence, based on observed residues (ATOM records): (download) 
    >3herA (A:)
lggyvlgsamsrpiihfgsdyedryyrenmhrypnqvyyrpmdeysnqnnfvhdcvniti
kqhtvtttstetdvkmmervveqmcitqyeresqayy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3herB (B:)
gqgggthsqwnkpskpktnmkhmagaaaagavvgglggyvlgsamsrpiihfgsdyedry
yrenmhrypnqvyyrpmdeysnqnnfvhdcvnitikqhtvttttkgenstetdvkmmerv
veqmcitqyeresqayyqrgss

    Sequence, based on observed residues (ATOM records): (download) 
    >3herB (B:)
ggyvlgsamsrpiihfgsdyedryyrenmhrypnqvyyrpmdeysnqnnfvhdcvnitik
qhtvtstetdvkmmervveqmcitqyeresqayyq