PDB entry 3hco
View 3hco on RCSB PDB site
Description: Human ferrochelatase with Cd and protoporphyrin IX bound
Class: lyase
Keywords: ferrochelatase, metal selectivity, Disease mutation, Heme biosynthesis, Iron, Iron-sulfur, Lyase, Membrane, Metal-binding, Mitochondrion, Mitochondrion inner membrane, Porphyrin biosynthesis, Transit peptide
Deposited on
2009-05-06, released
2009-11-10
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.21
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ferrochelatase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: FECH, hemH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3hcoa_ - Chain 'B':
Compound: Ferrochelatase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: FECH, hemH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3hcob_ - Heterogens: FES, GOL, IMD, BCT, CHD, HEM, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3hcoA (A:)
rkpktgilmlnmggpetlgdvhdfllrlfldrdlmtlpiqnklapfiakrrtpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadhilke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdhietlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3hcoB (B:)
rkpktgilmlnmggpetlgdvhdfllrlfldrdlmtlpiqnklapfiakrrtpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadhilke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdhietlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql