PDB entry 3ha8

View 3ha8 on RCSB PDB site
Description: THE COMPLEX STRUCTURE OF THE MAP KINASE P38/Compound 14b
Class: transferase
Keywords: TRANSFERASE, INHIBITOR, MAP KINASE, SERINE/ THREONINE-PROTEIN KINASE, P38, ATP-binding, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase
Deposited on 2009-05-01, released 2009-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: 0.217
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2, P38
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ha8a_
  • Heterogens: 5JZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ha8A (A:)
gsshhhhhhssglvprgshmsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaa
fdtktglrvavkklsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefnd
vylvthlmgadlnnivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavned
celkildfglarhtddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrt
lfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganpla
vdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsfesrdllidewkslt
ydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >3ha8A (A:)
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfdemtgyvatrwyra
peimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkki
ssesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaq
yhdpddepvadpydqsfesrdllidewksltydevisfvppp