PDB entry 3h6a

View 3h6a on RCSB PDB site
Description: Structure of the Calx-beta domain of integrin beta4 crystallized in the presence of calcium
Class: cell adhesion
Keywords: IMMUNOGLOBULIN FOLD, INTEGRIN, CELL ADHESION, EPIDERMOLYSIS BULLOSA, GLYCOPROTEIN, MEMBRANE, RECEPTOR, TRANSMEMBRANE, Alternative splicing, Disease mutation, Disulfide bond, Phosphoprotein, Polymorphism
Deposited on 2009-04-23, released 2009-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-08-04, with a file datestamp of 2009-07-31.
Experiment type: XRAY
Resolution: 1.61 Å
R-factor: 0.174
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrin beta-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGB4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16144 (4-End)
      • expression tag (3)
    Domains in SCOPe 2.08: d3h6aa1, d3h6aa2
  • Chain 'B':
    Compound: Integrin beta-4
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGB4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16144 (4-122)
      • expression tag (3)
    Domains in SCOPe 2.08: d3h6ab1, d3h6ab2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3h6aA (A:)
    gshmrdvvsfeqpefsvsrgdqvaripvirrvldggksqvsyrtqdgtaqgnrdyipveg
    ellfqpgeawkelqvkllelqevdsllrgrqvrrfhvqlsnpkfgahlgqphsttiiird
    pde
    

    Sequence, based on observed residues (ATOM records): (download)
    >3h6aA (A:)
    mrdvvsfeqpefsvsrgdqvaripvirrvldggksqvsyrtqdgtaqgnrdyipvegell
    fqpgeawkelqvkllelrqvrrfhvqlsnpkfgahlgqphsttiiirdp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3h6aB (B:)
    gshmrdvvsfeqpefsvsrgdqvaripvirrvldggksqvsyrtqdgtaqgnrdyipveg
    ellfqpgeawkelqvkllelqevdsllrgrqvrrfhvqlsnpkfgahlgqphsttiiird
    pde
    

    Sequence, based on observed residues (ATOM records): (download)
    >3h6aB (B:)
    mrdvvsfeqpefsvsrgdqvaripvirrvldggksqvsyrtqdgtaqgnrdyipvegell
    fqpgeawkelqvkllelllrgrqvrrfhvqlsnpkfgahlgqphsttiiirdpde