PDB entry 3h67

View 3h67 on RCSB PDB site
Description: Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c)with two Zn2+ atoms complexed with cantharidic acid
Class: Hydrolase
Keywords: metalloenzyme, phosphatase, inhibitors, drug design, Cytoplasm, Hydrolase, Iron, Manganese, Metal-binding, Nucleus, Protein phosphatase, TPR repeat
Deposited on 2009-04-23, released 2009-09-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-09-29, with a file datestamp of 2009-09-25.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.185
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase 5
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP5C, PPP5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3h67a_
  • Chain 'D':
    Compound: Serine/threonine-protein phosphatase 5
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP5C, PPP5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3h67d_
  • Heterogens: ZN, NHC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3h67A (A:)
ysgpkledgkvtisfmkelmqwykdqkklhrkcayqilvqvkevlsklstlvettlkete
kitvcgdthgqfydllnifelnglpsetnpyifngdfvdrgsfsveviltlfgfkllypd
hfhllrgnhetdnmnqiygfegevkakytaqmyelfsevfewlplaqcingkvlimhggl
fsedgvtlddirkiernrqppdsgpmcdllwsdpqpqngrsiskrgvscqfgpdvtkafl
eennldyiirshevkaegyevahggrcvtvfsapnycdqmgnkasyihlqgsdlrpqfhq
ftavphpnvkpmaya

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3h67D (D:)
ysgpkledgkvtisfmkelmqwykdqkklhrkcayqilvqvkevlsklstlvettlkete
kitvcgdthgqfydllnifelnglpsetnpyifngdfvdrgsfsveviltlfgfkllypd
hfhllrgnhetdnmnqiygfegevkakytaqmyelfsevfewlplaqcingkvlimhggl
fsedgvtlddirkiernrqppdsgpmcdllwsdpqpqngrsiskrgvscqfgpdvtkafl
eennldyiirshevkaegyevahggrcvtvfsapnycdqmgnkasyihlqgsdlrpqfhq
ftavphpnvkpmaya