PDB entry 3h5b

View 3h5b on RCSB PDB site
Description: Crystal structure of wild type HIV-1 protease with novel P1'-ligand GRL-02031
Class: hydrolase
Keywords: HIV-1, wild type protease, protease inhibitor, P1'-ligand, AIDS, Hydrolase
Deposited on 2009-04-21, released 2009-06-16
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: 0.144
AEROSPACI score: 0.79 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus type 1 (BRU ISOLATE) [TaxId:11686]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (94)
  Domains in SCOPe 2.02: d3h5ba_
• Chain 'B':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus type 1 (BRU ISOLATE) [TaxId:11686]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (94)
  Domains in SCOPe 2.02: d3h5bb_
• Heterogens: NA, CL, 031, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3h5bA (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3h5bB (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf