PDB entry 3h4k

View 3h4k on RCSB PDB site
Description: Crystal structure of the wild type Thioredoxin glutatione reductase from Schistosoma mansoni in complex with auranofin
Deposited on 2009-04-20, released 2009-08-25
The last revision was dated 2014-04-09, with a file datestamp of 2014-04-04.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.231
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thioredoxin glutathione reductase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: TGR
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, AU, K, GSH, PG4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3h4kA (A:)
    mppadgtsqwlrktvdsaavilfskttcpyckkvkdvlaeakikhatieldqlsngsaiq
    kclasfskietvpqmfvrgkfigdsqtvlkyysndelagivneskydydlivigggsggl
    aagkeaakygaktavldyveptpigttwglggtcvnvgcipkklmhqagllshaledaeh
    fgwsldrskishnwstmvegvqshigslnwgykvalrdnqvtylnakgrlisphevqitd
    knqkvstitgnkiilatgerpkypeipgaveygitsddlfslpyfpgktlvigasyvale
    cagflaslggdvtvmvrsillrgfdqqmaekvgdymenhgvkfaklcvpdeikqlkvvdt
    ennkpglllvkghytdgkkfeeefetvifavgrepqlskvlcetvgvkldkngrvvctdd
    eqttvsnvyaigdinagkpqltpvaiqagrylarrlfagateltdysnvattvftpleyg
    acglseedaiekygdkdievyhsnfkplewtvahrednvcymklvcrksdnmrvlglhvl
    gpnageitqgyavaikmgatkadfdrtigihptcsetfttlhvtkksgvspivsgcag
    

    Sequence, based on observed residues (ATOM records):
    >3h4kA (A:)
    gtsqwlrktvdsaavilfskttcpyckkvkdvlaeakikhatieldqlsngsaiqkclas
    fskietvpqmfvrgkfigdsqtvlkyysndelagivneskydydlivigggsgglaagke
    aakygaktavldyveptpigttwglggtcvnvgcipkklmhqagllshaledaehfgwsl
    drskishnwstmvegvqshigslnwgykvalrdnqvtylnakgrlisphevqitdknqkv
    stitgnkiilatgerpkypeipgaveygitsddlfslpyfpgktlvigasyvalecagfl
    aslggdvtvmvrsillrgfdqqmaekvgdymenhgvkfaklcvpdeikqlkvvdtennkp
    glllvkghytdgkkfeeefetvifavgrepqlskvlcetvgvkldkngrvvctddeqttv
    snvyaigdinagkpqltpvaiqagrylarrlfagateltdysnvattvftpleygacgls
    eedaiekygdkdievyhsnfkplewtvahrednvcymklvcrksdnmrvlglhvlgpnag
    eitqgyavaikmgatkadfdrtigihptcsetfttlhvtkksgvspiv