PDB entry 3h2a

View 3h2a on RCSB PDB site
Description: Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase
Class: Transferase/Transferase Inhibitor
Keywords: ANTHRACIS, FOLATE BIOSYNTHESIS, DIHYDROPTEROATE, PTERINE, Transferase, Transferase-Transferase Inhibitor COMPLEX
Deposited on 2009-04-14, released 2009-12-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.228
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydropteroate synthase
    Species: Bacillus anthracis str. A2012 [TaxId:191218]
    Gene: folP, BAO_0074
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3h2aa_
  • Chain 'B':
    Compound: dihydropteroate synthase
    Species: Bacillus anthracis str. A2012 [TaxId:191218]
    Gene: folP, BAO_0074
    Database cross-references and differences (RAF-indexed):
    • Uniprot B1UXN2 (20-End)
      • expression tag (3-16)
    Domains in SCOPe 2.06: d3h2ab1, d3h2ab2
  • Heterogens: B57, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3h2aA (A:)
    mgsshhhhhhssglvprgshmkwdydlrcgeytlnlnektlimgilnvtpdsfsdggsyn
    evdaavrhakemrdegahiidiggestrpgfakvsveeeikrvvpmiqavskevklpisi
    dtykaevakqaieagahiindiwgakaepkiaevaahydvpiilmhnrdnmnyrnlmadm
    iadlydsikiakdagvrdeniildpgigfaktpeqnleamrnleqlnvlgypvllgtsrk
    sfighvldlpveerlegtgatvclgiekgcefvrvhdvkemsrmakmmdamigkgvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3h2aA (A:)
    kwdydlrcgeytlnlnektlimgilnvtpdsfsgsynevdaavrhakemrdegahiidig
    gsveeeikrvvpmiqavskevklpisidtykaevakqaieagahiindiwgakaepkiae
    vaahydvpiilmhnrdnmnyrnlmadmiadlydsikiakdagvrdeniildpgigfaktp
    eqnleamrnleqlnvlgypvllgtsrksfighvldlpveerlegtgatvclgiekgcefv
    rvhdvkemsrmakmmdamigk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3h2aB (B:)
    mgsshhhhhhssglvprgshmkwdydlrcgeytlnlnektlimgilnvtpdsfsdggsyn
    evdaavrhakemrdegahiidiggestrpgfakvsveeeikrvvpmiqavskevklpisi
    dtykaevakqaieagahiindiwgakaepkiaevaahydvpiilmhnrdnmnyrnlmadm
    iadlydsikiakdagvrdeniildpgigfaktpeqnleamrnleqlnvlgypvllgtsrk
    sfighvldlpveerlegtgatvclgiekgcefvrvhdvkemsrmakmmdamigkgvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3h2aB (B:)
    shhhhhhssglvprmkwdydlrcgeytlnlnektlimgilnvtpggsynevdaavrhake
    mrdegahiidiggestvsveeeikrvvpmiqavskevklpisidtykaevakqaieagah
    iindiwgakaepkiaevaahydvpiilmhnrdnmnyrnlmadmiadlydsikiakdagvr
    deniildpgigfaktpeqnleamrnleqlnvlgypvllgtsrksfighvldlpveerleg
    tgatvclgiekgcefvrvhdvkemsrmakmmdamigk